The genome-wide expression profile of 1, 2, 3, 4, 6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism
WS Yu, SJ Jeong, JH Kim, HJ Lee, HS Song, MS Kim… - Molecules and …, 2011 - Springer
Abstract 1, 2, 3, 4, 6-penta-O-galloyl-beta-D-glucose (PGG), a polyphenolic compound
isolated from Rhus chinensis Mill. PGG has been known to have anti-tumor, anti-angiogenic …
isolated from Rhus chinensis Mill. PGG has been known to have anti-tumor, anti-angiogenic …
[HTML][HTML] Penta-O-galloyl-β-D-glucose induces G1arrest and DNA replicative S-phase arrest independently of P21 cyclin-dependent kinase inhibitor 1A, P27 cyclin …
Introduction Natural herbal compounds with novel actions different from existing breast
cancer (BCa) treatment modalities are attractive for improving therapeutic efficacy and …
cancer (BCa) treatment modalities are attractive for improving therapeutic efficacy and …
[HTML][HTML] In vitro study of anti-ER positive breast cancer effect and mechanism of 1, 2, 3, 4-6-pentyl-O-galloyl-beta-D-glucose (PGG)
Q Xiang, J Tang, Q Luo, J Xue, Y Tao, H Jiang… - Biomedicine & …, 2019 - Elsevier
Breast cancer is one of the most common malignancies and the leading cause of women's
death, most of breast cancers are estrogen receptor-positive (ER+) breast cancer which can …
death, most of breast cancers are estrogen receptor-positive (ER+) breast cancer which can …
[HTML][HTML] In vitro anti-hepatocellular carcinogenesis of 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose
Y Jiang, J Bi, M Wu, S Ye, L Hu, L Li, Y Yi… - Food & Nutrition …, 2023 - ncbi.nlm.nih.gov
Background 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose (β-PGG) is a polyphenol ellagic
compound with a variety of pharmacological effects and has an inhibitory effect on lots of …
compound with a variety of pharmacological effects and has an inhibitory effect on lots of …
[HTML][HTML] Pentagalloyl glucose inhibits TNF‐α‐activated CXCL1/GRO-α expression and induces apoptosis‐related genes in triple-negative breast cancer cells
P Mendonca, S Alghamdi, S Messeha, KFA Soliman - Scientific Reports, 2021 - nature.com
In triple-negative breast cancer (TNBC), the tumor microenvironment is associated with
increased proliferation, suppressing apoptotic mechanisms, an altered immune response …
increased proliferation, suppressing apoptotic mechanisms, an altered immune response …
[HTML][HTML] Apoptotic and DNA damage effect of 1, 2, 3, 4, 6-penta-O-galloyl-beta-D-glucose in cisplatin-resistant non-small lung cancer cells via phosphorylation of …
JH Kim, E Im, J Lee, HJ Lee, DY Sim, JE Park, CH Ahn… - Cells, 2022 - mdpi.com
Herein, the apoptotic mechanism of 1, 2, 3, 4, 6-penta-O-galloyl-β-D-glucopyranose (PGG)
was examined in cisplatin-resistant lung cancer cells. PGG significantly reduced viability; …
was examined in cisplatin-resistant lung cancer cells. PGG significantly reduced viability; …
Penta- O -galloyl-beta- d -glucose suppresses tumor growth via inhibition of angiogenesis and stimulation of apoptosis: roles of …
Recent studies have revealed that 1, 2, 3, 4, 6-penta-O-galloyl-beta-d-glucose (PGG) has
anti-tumorigenic activity in vitro. In the present work, we evaluated the in vitro and in vivo …
anti-tumorigenic activity in vitro. In the present work, we evaluated the in vitro and in vivo …
[HTML][HTML] Microarray analysis of breast cancer gene expression profiling in response to 2-deoxyglucose, metformin, and glucose starvation
R Aoun, C El Hadi, R Tahtouh, R El Habre… - Cancer Cell …, 2022 - Springer
Background Breast cancer (BC) is the most frequently diagnosed cancer in women. Altering
glucose metabolism and its effects on cancer progression and treatment resistance is an …
glucose metabolism and its effects on cancer progression and treatment resistance is an …
[HTML][HTML] 1,2,3,4,6-Penta-O-galloyl-d-glucose Interrupts the Early Adipocyte Lifecycle and Attenuates Adiposity and Hepatic Steatosis in Mice with Diet-Induced Obesity
AR Sathyanarayana, CK Lu, CC Liaw… - International journal of …, 2022 - mdpi.com
Phytochemicals that interrupt adipocyte lifecycle can provide anti-obesity effects. 1, 2, 3, 4, 6-
penta-O-galloyl-d-glucose (PGG) is a tannin with two isomers that occurs widely in plants …
penta-O-galloyl-d-glucose (PGG) is a tannin with two isomers that occurs widely in plants …
[HTML][HTML] Phloridzin docosahexaenoate inhibits spheroid formation by breast cancer stem cells and exhibits cytotoxic effects against paclitaxel-resistant triple negative …
W Fernando, RF Clark, HPV Rupasinghe… - International Journal of …, 2023 - mdpi.com
The eradication of cancer stem cells (CSCs) is vital to successful cancer treatment and
overall disease-free survival. CSCs are a sub-population of cells within a tumor that are …
overall disease-free survival. CSCs are a sub-population of cells within a tumor that are …
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