A plethora of physiological and pathological stimuli induce and activate a group of DNA
binding proteins that form AP-1 dimers. These proteins include the Jun, Fos and ATF …

The AP2 transcription factor family is a set of developmentally regulated, retinoic acid
inducible genes composed of four related factors, AP2α, AP2β, AP2γ, and AP2δ. AP2 factors …

The transcription factor AP-1 (activator protein-1) is involved in cellular proliferation,
transformation and death. Using mice and cells lacking AP-1 components, the target-genes …

Genetically modified mice have provided important insights into the biological functions of
the dimeric transcription factor complex AP-1. Extensive analyses of mice and cells with …

The AP-1 transcription factor is a dimeric complex that contains members of the JUN, FOS,
ATF and MAF protein families. AP-1 proteins are primarily considered to be oncogenic, but …

The AP-1 transcription factor is composed of a mixture of homo-and hetero-dimers formed
between Jun and Fos proteins. The different Jun and Fos family members vary significantly …

Since its discovery more than two decades ago the involvement of the Activating protein 1
(AP-1) in proliferation, inflammation, differentiation, apoptosis, cellular migration and wound …

This issue attempts to give a 'state of the art'overview of the AP-1 transcription factor family, a
fundamental class of transcriptional regulators. The AP-1 family consists of several bZIP …

Multi-gene families of transcription factors pose a formidable challenge to molecular and
functional analysis. Dissecting distinct functions for individual family members requires a …

The nuclear transcription factor AP-1, composed of dimers of Fos and Jun proteins, has
been linked to a startling breadth of cellular events including cell transformation …