The natural (poly) phenols as modulators of microglia polarization via TLR4/NF-κB pathway exert anti-inflammatory activity in ischemic stroke
R Li, Y Zhou, S Zhang, J Li, Y Zheng, X Fan - European journal of …, 2022 - Elsevier
Increasing evidences suggest that inflammation plays a key role in the pathogenesis of
stroke, a devastating disease second only to cardiac ischemia as a cause of death …
stroke, a devastating disease second only to cardiac ischemia as a cause of death …
Phytochemicals as regulators of microglia/macrophages activation in cerebral ischemia
The search for novel therapeutic agents for the management of cerebral ischemia/stroke has
become an appealing research interest in the recent past. Neuroprotective phytochemicals …
become an appealing research interest in the recent past. Neuroprotective phytochemicals …
Anti-inflammatory effects of anisalcohol on lipopolysaccharide-stimulated BV2 microglia via selective modulation of microglia polarization and down-regulation of NF …
B Xiang, C Xiao, T Shen, X Li - Molecular immunology, 2018 - Elsevier
Inflammation plays a pivotal role in the pathogenesis of ischemic stroke. The inhibition of
inflammation appears to be a potential therapeutic strategy for neuro-inflammatory injury …
inflammation appears to be a potential therapeutic strategy for neuro-inflammatory injury …
Modulators of microglia activation and polarization in ischemic stroke
CT Jiang, WF Wu, YH Deng… - Molecular medicine …, 2020 - spandidos-publications.com
Ischemic stroke is one of the leading causes of mortality and disability worldwide. However,
there is a current lack of effective therapies available. As the resident macrophages of the …
there is a current lack of effective therapies available. As the resident macrophages of the …
[HTML][HTML] Quercetin improves cerebral ischemia/reperfusion injury by promoting microglia/macrophages M2 polarization via regulating PI3K/Akt/NF-κB signaling …
L Li, W Jiang, B Yu, H Liang, S Mao, X Hu… - Biomedicine & …, 2023 - Elsevier
The modulation of microglial polarization from the pro-inflammatory M1 to the anti-
inflammatory M2 phenotype shows promise as a therapeutic strategy for ischemic stroke …
inflammatory M2 phenotype shows promise as a therapeutic strategy for ischemic stroke …
Microglia and monocytes/macrophages polarization reveal novel therapeutic mechanism against stroke
M Kanazawa, I Ninomiya, M Hatakeyama… - International journal of …, 2017 - mdpi.com
Stroke is a leading cause of morbidity and mortality worldwide, and consists of two types,
ischemic and hemorrhagic. Currently, there is no effective treatment to increase the survival …
ischemic and hemorrhagic. Currently, there is no effective treatment to increase the survival …
Role of dietary phenols in mitigating microglia-mediated neuroinflammation
P Rangarajan, A Karthikeyan, ST Dheen - Neuromolecular medicine, 2016 - Springer
Chronic neuroinflammation is a pathological feature of a number of central nervous system
(CNS) diseases and is mediated by sustained activation of microglial cells, the innate …
(CNS) diseases and is mediated by sustained activation of microglial cells, the innate …
Regulation of microglia polarization after cerebral ischemia
H Wang, J Li, H Zhang, M Wang, L Xiao… - Frontiers in Cellular …, 2023 - frontiersin.org
Stroke ranks second as a leading cause of death and permanent disability globally.
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …
[HTML][HTML] Effects of microglial activation and polarization on brain injury after stroke
R Dong, R Huang, J Wang, H Liu, Z Xu - Frontiers in neurology, 2021 - frontiersin.org
Stroke is one of the most common causes of death worldwide. The subsequent development
of neuroinflammation and brain edema dramatically increases the risks associated with …
of neuroinflammation and brain edema dramatically increases the risks associated with …
A dual AMPK/Nrf2 activator reduces brain inflammation after stroke by enhancing microglia M2 polarization
Y Wang, Y Huang, Y Xu, W Ruan, H Wang… - Antioxidants & redox …, 2018 - liebertpub.com
Aims: Microglia-mediated neuroinflammation plays an important role in focal ischemic
stroke, a disorder with no effective therapeutic agents. Since microglial polarization to the …
stroke, a disorder with no effective therapeutic agents. Since microglial polarization to the …
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