Exogenous brain-derived neurotrophic factor rescues synaptic dysfunction in Mecp2-null mice
DD Kline, M Ogier, DL Kunze… - Journal of Neuroscience, 2010 - Soc Neuroscience
Postnatal deficits in brain-derived neurotrophic factor (BDNF) are thought to contribute to
pathogenesis of Rett syndrome (RTT), a progressive neurodevelopmental disorder caused …
pathogenesis of Rett syndrome (RTT), a progressive neurodevelopmental disorder caused …
Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome
M Ogier, H Wang, E Hong, Q Wang… - Journal of …, 2007 - Soc Neuroscience
Rett syndrome (RTT) is caused by loss-of-function mutations in the gene encoding methyl-
CpG-binding protein 2 (MeCP2). Although MeCP2 is thought to act as a transcriptional …
CpG-binding protein 2 (MeCP2). Although MeCP2 is thought to act as a transcriptional …
Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice
H Wang, S Chan, M Ogier, D Hellard… - Journal of …, 2006 - Soc Neuroscience
Disruptions in brain-derived neurotrophic factor (BDNF) expression are proposed to
contribute to the molecular pathogenesis of Rett syndrome (RTT), a severe neurological …
contribute to the molecular pathogenesis of Rett syndrome (RTT), a severe neurological …
Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice
W Li, G Calfa, J Larimore… - Proceedings of the …, 2012 - National Acad Sciences
Dysfunction of the neurotrophin brain-derived neurotrophic factor (BDNF) is implicated in
Rett syndrome (RTT), but the state of its releasable pool and downstream signaling in mice …
Rett syndrome (RTT), but the state of its releasable pool and downstream signaling in mice …
A BDNF loop-domain mimetic acutely reverses spontaneous apneas and respiratory abnormalities during behavioral arousal in a mouse model of Rett syndrome
M Kron, M Lang, IT Adams, M Sceniak… - Disease Models & …, 2014 - journals.biologists.com
Reduced levels of brain-derived neurotrophic factor (BDNF) are thought to contribute to the
pathophysiology of Rett syndrome (RTT), a severe neurodevelopmental disorder caused by …
pathophysiology of Rett syndrome (RTT), a severe neurodevelopmental disorder caused by …
Brain-derived neurotrophic factor and Rett syndrome
DM Katz - Neurotrophic Factors, 2014 - Springer
Rett syndrome (RTT) is a devastating neurodevelopmental disorder with autistic features
caused by loss-of-function mutations in the gene encoding methyl-CpG-binding protein 2 …
caused by loss-of-function mutations in the gene encoding methyl-CpG-binding protein 2 …
The ups and downs of BDNF in Rett syndrome
YE Sun, H Wu - Neuron, 2006 - cell.com
Rett syndrome (RTT) is an X-linked postnatal neurodevelopmental disorder, which is
primarily caused by mutations in the gene encoding methyl-CpG binding protein 2 (MeCP2) …
primarily caused by mutations in the gene encoding methyl-CpG binding protein 2 (MeCP2) …
Loss of MeCP2 disrupts cell autonomous and autocrine BDNF signaling in mouse glutamatergic neurons
C Sampathkumar, YJ Wu, M Vadhvani, T Trimbuch… - Elife, 2016 - elifesciences.org
Mutations in the MECP2 gene cause the neurodevelopmental disorder Rett syndrome
(RTT). Previous studies have shown that altered MeCP2 levels result in aberrant neurite …
(RTT). Previous studies have shown that altered MeCP2 levels result in aberrant neurite …
A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome
DA Schmid, T Yang, M Ogier, I Adams… - Journal of …, 2012 - Soc Neuroscience
Rett syndrome (RTT) results from loss-of-function mutations in the gene encoding the methyl-
CpG-binding protein 2 (MeCP2) and is characterized by abnormal motor, respiratory and …
CpG-binding protein 2 (MeCP2) and is characterized by abnormal motor, respiratory and …
[HTML][HTML] The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression
Q Chang, G Khare, V Dani, S Nelson, R Jaenisch - Neuron, 2006 - cell.com
Mutations in the MECP2 gene cause Rett syndrome (RTT). Bdnf is a MeCP2 target gene;
however, its role in RTT pathogenesis is unknown. We examined Bdnf conditional mutant …
however, its role in RTT pathogenesis is unknown. We examined Bdnf conditional mutant …