Sick and tired: does sleep have a vital role in the immune system?

PA Bryant, J Trinder, N Curtis - Nature Reviews Immunology, 2004 - nature.com
It is a common belief that we are more susceptible to infections when deprived of sleep.
Consistent with this, there is increasing evidence that sleep deprivation has detrimental …

The bidirectional relationship between sleep and immunity against infections

EG Ibarra-Coronado… - Journal of …, 2015 - Wiley Online Library
Sleep is considered an important modulator of the immune response. Thus, a lack of sleep
can weaken immunity, increasing organism susceptibility to infection. For instance, shorter …

Impact of partial sleep deprivation on immune markers

A Wilder-Smith, FB Mustafa, A Earnest, L Gen… - Sleep medicine, 2013 - Elsevier
Background Sleep quality is considered to be an important predictor of immunity. Lack of
sleep therefore may reduce immunity, thereby increasing the susceptibility to respiratory …

Sleep as a host defense: its regulation by microbial products and cytokines

JM Krueger, JA Majde - Clinical immunology and immunopathology, 1990 - Elsevier
Fatigue and excess sleep, combined with fever, are presenting symptoms in nearly all
infectious diseases and chronic inflammatory disorders. Fever, because it is easily …

Sleep, sleep deprivation and infectious disease: studies in animals

LA Toth - Advances in neuroimmunology, 1995 - Elsevier
Common perceptions that the desire for sleep is increased during mild infectious diseases
like colds and 'the flu'have fostered beliefs that sleep promotes recovery from infectious …

The sleep-immune crosstalk in health and disease

L Besedovsky, T Lange, M Haack - Physiological reviews, 2019 - journals.physiology.org
Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Role of sleep deprivation in immune-related disease risk and outcomes

S Garbarino, P Lanteri, NL Bragazzi… - Communications …, 2021 - nature.com
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …

Sleep loss as a factor to induce cellular and molecular inflammatory variations

G Hurtado-Alvarado, L Pavón… - Journal of …, 2013 - Wiley Online Library
A reduction in the amount of time spent sleeping occurs chronically in modern society.
Clinical and experimental studies in humans and animal models have shown that immune …

[引用][C] Sleep deprivation and human immune function

DF Dinges, SD Douglas, S Hamarman, L Zaugg… - Advances in …, 1995 - Elsevier
Sleep is a fundamental biological need in humans. Sleep deprivation from medical and
psychiatric conditions, as well as from life style (eg shift work, jet lag) is endemic in modern …

Sleep, immunity, and circadian clocks: a mechanistic model

T Bollinger, A Bollinger, H Oster, W Solbach - Gerontology, 2010 - karger.com
The lack of sufficient amounts of sleep is a hallmark of modern living, and it is commonly
perceived that in the long run this makes us sick. An increasing amount of scientific data …