The potential remedy of melatonin on osteoarthritis
KH Lu, PWA Lu, EWH Lu, CH Tang… - Journal of Pineal …, 2021 - Wiley Online Library
Osteoarthritis (OA), the most common arthritis worldwide, is a degenerative joint disease
characterized by progressive cartilage breakdown, subchondral remodeling, and synovial …
characterized by progressive cartilage breakdown, subchondral remodeling, and synovial …
Melatonin: A novel candidate for the treatment of osteoarthritis
Y Zhang, T Liu, H Yang, F He, X Zhu - Ageing research reviews, 2022 - Elsevier
Osteoarthritis (OA), characterized by cartilage erosion, synovium inflammation, and
subchondral bone remodeling, is a common joint degenerative disease worldwide. OA …
subchondral bone remodeling, is a common joint degenerative disease worldwide. OA …
Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes
R Jahanban‐Esfahlan, S Mehrzadi… - British journal of …, 2018 - Wiley Online Library
Rheumatoid arthritis (RA) and osteoarthritis (OA) are the two most prevalent joint diseases.
A such, they are important causes of pain and disability in a substantial proportion of the …
A such, they are important causes of pain and disability in a substantial proportion of the …
Melatonin attenuates TNF‐α and IL‐1β expression in synovial fibroblasts and diminishes cartilage degradation: Implications for the treatment of rheumatoid arthritis
CC Huang, CH Chiou, SC Liu, SL Hu… - Journal of pineal …, 2019 - Wiley Online Library
The hormone melatonin has many properties, including antioxidant, anti‐inflammatory, and
immunomodulatory effects. Melatonin has been demonstrated to be beneficial in several …
immunomodulatory effects. Melatonin has been demonstrated to be beneficial in several …
Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin
A Hosseinzadeh, SK Kamrava… - Journal of pineal …, 2016 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …
[HTML][HTML] Role of melatonin combined with exercise as a switch-like regulator for circadian behavior in advanced osteoarthritic knee
Y Hong, H Kim, S Lee, Y Jin, J Choi, SR Lee… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Here, we show the role of melatonin combined with or without exercise as a determinant of
multicellular behavior in osteoarthritis. We address the relationship between the molecular …
multicellular behavior in osteoarthritis. We address the relationship between the molecular …
Reconsidering the role of melatonin in rheumatoid arthritis
Rheumatoid arthritis (RA) is an inflammatory joint disorder characterized by synovial
proliferation and inflammation, with eventual joint destruction if inadequately treated …
proliferation and inflammation, with eventual joint destruction if inadequately treated …
Melatonin abolished proinflammatory factor expression and antagonized osteoarthritis progression in vivo
Progressive structural changes in osteoarthritis (OA) involve synovial inflammation and
angiogenesis, as well as activation of the proinflammatory cytokines tumor necrosis factor …
angiogenesis, as well as activation of the proinflammatory cytokines tumor necrosis factor …
Melatonin prevents osteoarthritis‐induced cartilage degradation via targeting MicroRNA‐140
Y Zhang, J Lin, X Zhou, X Chen… - Oxidative medicine …, 2019 - Wiley Online Library
Osteoarthritis (OA) is characterized by the progressive destruction of articular cartilage,
which is involved in the imbalance between extracellular matrix (ECM) synthesis and …
which is involved in the imbalance between extracellular matrix (ECM) synthesis and …
Physiological and pathological role of circadian hormones in osteoarthritis: dose-dependent or time-dependent?
FM Hossain, Y Hong, Y Jin, J Choi, Y Hong - Journal of clinical medicine, 2019 - mdpi.com
Osteoarthritis (OA), the most common form of arthritis, may be triggered by improper
secretion of circadian clock-regulated hormones, such as melatonin, thyroid-stimulating …
secretion of circadian clock-regulated hormones, such as melatonin, thyroid-stimulating …