Importance of dietary phosphorus for bone metabolism and healthy aging

J Serna, C Bergwitz - Nutrients, 2020 - mdpi.com
Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

Is phosphorus intake that exceeds dietary requirements a risk factor in bone health?

MS Calvo, KL Tucker - Annals of the New York Academy of …, 2013 - Wiley Online Library
Phosphorus intake in excess of the nutrient needs of healthy adults is thought to disrupt
hormonal regulation of phosphorus (P), calcium (Ca), and vitamin D, contributing to impaired …

The basics of phosphate metabolism

CA Wagner - Nephrology Dialysis Transplantation, 2024 - academic.oup.com
Phosphorus is an essential mineral that is, in the form of inorganic phosphate (Pi), required
for building cell membranes, DNA and RNA molecules, energy metabolism, signal …

Phosphate as a signaling molecule

K Kritmetapak, R Kumar - Calcified tissue international, 2021 - Springer
Phosphorus plays a vital role in diverse biological processes including intracellular
signaling, membrane integrity, and skeletal biomineralization; therefore, the regulation of …

[HTML][HTML] Assessing the health impact of phosphorus in the food supply: issues and considerations

MS Calvo, AJ Moshfegh, KL Tucker - Advances in Nutrition, 2014 - Elsevier
The Western dietary pattern of intake common to many Americans is high in fat, refined
carbohydrates, sodium, and phosphorus, all of which are associated with processed food …

Dietary phosphorus in bone health and quality of life

E Takeda, H Yamamoto… - Nutrition …, 2012 - academic.oup.com
Awareness of phosphorus intake is important because both phosphorus deficiency and
overloading impair bone health and quality of life. Phosphorus consumption is increasing in …

Effects of excessive dietary phosphorus intake on bone health

CJ Vorland, ER Stremke, RN Moorthi… - Current osteoporosis …, 2017 - Springer
Abstract Purpose of Review The purpose of this review is to provide an overview of dietary
phosphorus, its sources, recommended intakes, and its absorption and metabolism in health …

The regulation and function of phosphate in the human body

E Takeda, Y Taketani, N Sawada, T Sato… - Biofactors, 2004 - Wiley Online Library
Inorganic phosphate (Pi) is required for cellular function and skeletal mineralization. Serum
Pi level is maintained within a narrow range through a complex interplay between intestinal …

Calcium and phosphate: a duet of ions playing for bone health

JP Bonjour - Journal of the American College of Nutrition, 2011 - Taylor & Francis
The acquisition and maintenance of bone mass and strength are influenced by
environmental factors, including physical activity and nutrition. Among micronutrients …

Phosphate as a signaling molecule and its sensing mechanism

T Michigami, M Kawai, M Yamazaki… - Physiological …, 2018 - journals.physiology.org
In mammals, phosphate balance is maintained by influx and efflux via the intestines,
kidneys, bone, and soft tissue, which involves multiple sodium/phosphate (Na+/Pi) …