Background Cerebral small vessel disease (CSVD) comprises a variety of disorders
affecting small arteries and microvessels of the brain, manifesting as white matter …

Alzheimer's disease (AD) is the most common cause of dementia. Despite this, clear
pathophysiology for AD has not been confirmed, and effective treatments are still not …

Importance It remains unclear if and how associations between cerebral small-vessel
disease and Alzheimer disease (AD) pathology lead to cognitive decline and dementia …

Background: Cerebral small vessel disease (SVD) is one of the major contributors to
cognitive impairment and dementia. However, data on the incidence and progression of …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

The association between cerebral small vessel disease (SVD)–in the form of white matter
lesions, infarctions, and hemorrhages–with vascular cognitive impairment (VCI), has mostly …

Introduction Cerebral small vessel disease is increasingly linked to dementia. Methods We
systematically searched Medline, Embase, and Cochrane databases for prospective …

Background Considerable overlap exists between the risk factors of dementia and cerebral
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …

MRI features of cerebral small vessel disease (CSVD), ie white matter hyperintensities,
lacunes, microbleeds, perivascular spaces, and cerebral atrophy, may be associated with …

Background: The relationship between cerebral small vessel disease (SVD) and dementia
has been studied without considering white matter (WM) volume, the microstructural integrity …