The subthalamic nucleus: unravelling new roles and mechanisms in the control of action

T Bonnevie, KA Zaghloul - The Neuroscientist, 2019 - journals.sagepub.com
How do we decide what we do? This is the essence of action control, the process of
selecting the most appropriate response among multiple possible choices. Suboptimal …

Inhibitory control and error monitoring by human subthalamic neurons

J Bastin, M Polosan, D Benis, L Goetz… - Translational …, 2014 - nature.com
The subthalamic nucleus (STN) has been shown to be implicated in the control of voluntary
action, especially during tasks involving conflicting choice alternatives or rapid response …

[HTML][HTML] Deep brain stimulation and recordings: insights into the contributions of subthalamic nucleus in cognition

NM Drummond, R Chen - Neuroimage, 2020 - Elsevier
Recent progress in targeted interrogation of basal ganglia structures and networks with
deep brain stimulation in humans has provided insights into the complex functions the …

Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation

CP Mosher, AN Mamelak, M Malekmohammadi… - Neuron, 2021 - cell.com
The subthalamic nucleus (STN) supports action selection by inhibiting all motor programs
except the desired one. Recent evidence suggests that STN can also cancel an already …

The subthalamic nucleus

MD Bevan - Handbook of Behavioral Neuroscience, 2016 - Elsevier
The glutamatergic subthalamic nucleus (STN) is a key node in the cortico-basal ganglia-
thalamo-cortical circuit. As a component of the hyperdirect and indirect pathways, the STN is …

The subthalamic nucleus, oscillations, and conflict

B Zavala, K Zaghloul, P Brown - Movement Disorders, 2015 - Wiley Online Library
The subthalamic nucleus (STN), which is currently the most common target for deep brain
stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the …

Frontal cortex-like functions of the subthalamic nucleus

C Baunez, S Lardeux - Frontiers in systems neuroscience, 2011 - frontiersin.org
The subthalamic nucleus (STN) has been considered a motor structure for a long time. Over
the last 20 years, anatomical and behavioral data have highlighted the position of the STN …

Unilateral stimulation of subthalamic nucleus does not affect inhibitory control

C Mancini, N Modugno, M Santilli, L Pavone… - Frontiers in …, 2019 - frontiersin.org
Despite the relevance of inhibitory control in shaping our behavior its neural substrates are
still hotly debated. In this regard, it has been suggested that inhibitory control relies upon a …

Subthalamic nucleus activity influences sensory and motor cortex during force transduction

A Alhourani, A Korzeniewska, TA Wozny… - Cerebral …, 2020 - academic.oup.com
The subthalamic nucleus (STN) is proposed to participate in pausing, or alternately, in
dynamic scaling of behavioral responses, roles that have conflicting implications for …

The subthalamic nucleus, limbic function, and impulse control

PJ Rossi, A Gunduz, MS Okun - Neuropsychology review, 2015 - Springer
It has been well documented that deep brain stimulation (DBS) of the subthalamic nucleus
(STN) to address some of the disabling motor symptoms of Parkinson's disease (PD) can …