[HTML][HTML] Translational studies on the potential of a VEGF nanoparticle-loaded hyaluronic acid hydrogel
Heart failure has a five-year mortality rate approaching 50%. Inducing angiogenesis
following a myocardial infarction is hypothesized to reduce cardiomyocyte death and tissue …
following a myocardial infarction is hypothesized to reduce cardiomyocyte death and tissue …
Development of a nanomedicine-loaded hydrogel for sustained delivery of an angiogenic growth factor to the ischaemic myocardium
The 5-year mortality rate for heart failure borders on 50%. The main cause is an ischaemic
cardiac event where blood supply to the tissue is lost and cell death occurs. Over time, this …
cardiac event where blood supply to the tissue is lost and cell death occurs. Over time, this …
Dual delivery of VEGF and ANG-1 in ischemic hearts using an injectable hydrogel
AJ Rufaihah, NA Johari, SR Vaibavi, M Plotkin… - Acta biomaterialia, 2017 - Elsevier
Acute myocardial infarction (MI) caused by ischemia is the most common cause of cardiac
dysfunction. While growth factor therapy is promising, the retention in the highly vascularized …
dysfunction. While growth factor therapy is promising, the retention in the highly vascularized …
Induction of angiogenesis by controlled delivery of vascular endothelial growth factor using nanoparticles
J Xie, H Wang, Y Wang, F Ren, W Yi… - Cardiovascular …, 2013 - Wiley Online Library
Aims The study reports the feasibility and efficiency of vascular endothelial growth factor
(VEGF) delivery using nanoparticles synthesized from glycidyl methacrylated dextran (D ex …
(VEGF) delivery using nanoparticles synthesized from glycidyl methacrylated dextran (D ex …
Sustained VEGF delivery via PLGA nanoparticles promotes vascular growth
Technologies to increase tissue vascularity are critically important to the fields of tissue
engineering and cardiovascular medicine. Currently, limited technologies exist to encourage …
engineering and cardiovascular medicine. Currently, limited technologies exist to encourage …
[HTML][HTML] Dual delivery of hepatocyte and vascular endothelial growth factors via a protease-degradable hydrogel improves cardiac function in rats
Acute myocardial infarction (MI) caused by ischemia and reperfusion (IR) is the most
common cause of cardiac dysfunction due to local cell death and a temporally regulated …
common cause of cardiac dysfunction due to local cell death and a temporally regulated …
[HTML][HTML] Comparison of the effect of two hyaluronic acid preparations on fibroblast and endothelial cell functions related to angiogenesis
V Ciccone, M Zazzetta, L Morbidelli - Cells, 2019 - mdpi.com
Hyaluronic acid (HA) is used in substitutive and aesthetic medicine with various
applications. Ultrapure absorbable HA (Bioregen®) and a mix of reticulated and free low …
applications. Ultrapure absorbable HA (Bioregen®) and a mix of reticulated and free low …
Efficient revascularization by VEGF administration via heparin-functionalized nanoparticle–fibrin complex
YI Chung, SK Kim, YK Lee, SJ Park, KO Cho… - Journal of Controlled …, 2010 - Elsevier
We investigated the angiogenic bioactivity and therapeutic angiogenic effect of vascular
endothelial growth factor (VEGF) administration by the heparin-functionalized nanoparticle …
endothelial growth factor (VEGF) administration by the heparin-functionalized nanoparticle …
A novel protein‐engineered hepatocyte growth factor analog released via a shear‐thinning injectable hydrogel enhances post‐infarction ventricular function
AN Steele, L Cai, VN Truong… - Biotechnology and …, 2017 - Wiley Online Library
In the last decade, numerous growth factors and biomaterials have been explored for the
treatment of myocardial infarction (MI). While pre‐clinical studies have demonstrated …
treatment of myocardial infarction (MI). While pre‐clinical studies have demonstrated …
VEGF nanoparticles repair the heart after myocardial infarction
Vascular endothelial growth factor (VEGF) is a well-characterized proangiogenic cytokine
that has been shown to promote neovascularization in hearts of patients with ischemic heart …
that has been shown to promote neovascularization in hearts of patients with ischemic heart …