Background The ability to accurately predict early progression of dengue to severe disease
is crucial for patient triage and clinical management. Previous systematic reviews and meta …

Highlights•Biomarkers of severe dengue can potentially improve clinical dengue outcomes
and alleviate the healthcare burden in dengue-endemic settings.•Risk factors for severe …

Background The burden of dengue continues to increase globally, with an estimated 100
million clinically apparent infections occurring each year. Although most dengue infections …

Background Dengue is a major public health issue worldwide and severe dengue (SD) is
life threatening. It is critical to triage patients with dengue infection in the early stage …

Early identification of dengue patients at risk of adverse outcomes is important to prevent
hospital overcrowding in low-to middle-income countries during epidemics. We performed a …

Introduction: Dengue is a major public health problem in Singapore. Age-specific dengue
morbidity rates are highest in the young adult population, unlike in many other Southeast …

Background The WHO guidelines were revised recently to identify patients with severe
dengue (SD) early. We proceeded to determine the usefulness of the warning signs in the …

Background Severe dengue is a life-threatening complication; rapid identification of these
cases, followed by adequate management is crucial to improve the clinical prognosis …

The aim of the meta‐analysis was to provide more solid evidence for the reliability of the
new classification. A systematic literature search was performed using PubMed, Armed …

Background The mean age of acute dengue has undergone a shift towards older ages. This
fact points towards the relevance of assessing the influence of age-related comorbidities …