Artificial intelligence‐driven consensus gene signatures for improving bladder cancer clinical outcomes identified by multi‐center integration analysis

H Xu, Z Liu, S Weng, Q Dang, X Ge, Y Zhang… - Molecular …, 2022 - Wiley Online Library
To accurately predict the prognosis and further improve the clinical outcomes of bladder
cancer (BLCA), we leveraged large‐scale data to develop and validate a robust signature …

[HTML][HTML] Prognosis stratification and personalized treatment in bladder cancer through a robust immune gene pair‐based signature

X Lu, J Meng, J Zhu, Y Zhou, L Jiang… - Clinical and …, 2021 - ncbi.nlm.nih.gov
To the Editor: Numerous prognostic signatures to bladder cancer (BCa) have been reported,
but many of them limited to either nonmuscle-invasive (NMIBC) or muscle-invasive BCa …

[HTML][HTML] Identification and validation of an individualized prognostic signature of bladder cancer based on seven immune related genes

H Qiu, X Hu, C He, B Yu, Y Li, J Li - Frontiers in genetics, 2020 - frontiersin.org
Background There has been no report of prognostic signature based on immune-related
genes (IRGs). This study aimed to develop an IRG-based prognostic signature that could …

[HTML][HTML] A risk score staging system based on the expression of seven genes predicts the outcome of bladder cancer

J Chu, N Li, F Li - Oncology Letters, 2018 - spandidos-publications.com
Bladder cancer (BLCA) is among the most malignant types of cancer. At present, the
prognostic tools available for this disease are insufficient. In the present study, the …

Combination of a novel gene expression signature with a clinical nomogram improves the prediction of survival in high-risk bladder cancer

M Riester, JM Taylor, A Feifer, T Koppie… - Clinical cancer …, 2012 - AACR
Purpose: We aimed to validate and improve prognostic signatures for high-risk urothelial
carcinoma of the bladder. Experimental Design: We evaluated microarray data from 93 …

[HTML][HTML] A novel gene signature combination improves the prediction of overall survival in urinary bladder cancer

S Chen, N Zhang, J Shao, T Wang, X Wang - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Objectives: Bladder carcinoma is a clinical heterogeneous disease, which is with significant
variability of the prognosis and high risk of death. This revealed prominently the need to …

Clinical use of machine learning‐based pathomics signature for diagnosis and survival prediction of bladder cancer

S Chen, L Jiang, X Zheng, J Shao, T Wang… - Cancer …, 2021 - Wiley Online Library
Traditional histopathology performed by pathologists by the naked eye is insufficient for
accurate and efficient diagnosis of bladder cancer (BCa). We collected 643 H&E‐stained …

[HTML][HTML] Development and validation of a six-gene prognostic signature for bladder cancer

F Xu, Q Tang, Y Wang, G Wang, K Qian, L Ju… - Frontiers in …, 2021 - frontiersin.org
Human bladder cancer (BCa) is the most common urogenital system malignancy. Patients
with BCa have limited treatment efficacy in clinical practice. Novel biomarkers could provide …

[HTML][HTML] Development and external validation of a novel 12-gene signature for prediction of overall survival in muscle-invasive bladder cancer

MX Abudurexiti, H Xie, Z Jia, Y Zhu, Y Zhu, G Shi… - Frontiers in …, 2019 - frontiersin.org
Purpose: We aimed to develop and validate a novel gene signature from published data and
improve the prediction of survival in muscle-invasive bladder cancer (MIBC). Methods: We …

[HTML][HTML] Identification of a tumor microenvironment-related seven-gene signature for predicting prognosis in bladder cancer

Z Wang, L Tu, M Chen, S Tong - BMC cancer, 2021 - Springer
Background Accumulating evidences demonstrated tumor microenvironment (TME) of
bladder cancer (BLCA) may play a pivotal role in modulating tumorigenesis, progression …