Recent advances in the epithelial barrier theory
The epithelial barrier theory links the recent rise in chronic non-communicable diseases,
notably autoimmune and allergic disorders, to environmental agents disrupting the epithelial …
notably autoimmune and allergic disorders, to environmental agents disrupting the epithelial …
[PDF][PDF] The epithelial barrier hypothesis: a 20-year journey
The global environment has been transformed rapidly in the last six decades as a direct
result of a more westernized, industrialized, and modernized world. At the same time …
result of a more westernized, industrialized, and modernized world. At the same time …
The epithelial barrier theory: development and exacerbation of allergic and other chronic inflammatory diseases
It is now longer than half a century, humans, animals, and nature of the world are under the
influence of exposure to many newly introduced noxious substances. These exposures are …
influence of exposure to many newly introduced noxious substances. These exposures are …
Environmental factors in epithelial barrier dysfunction
The main interfaces controlling and attempting to homeostatically balance communications
between the host and the environment are the epithelial barriers of the skin, gastrointestinal …
between the host and the environment are the epithelial barriers of the skin, gastrointestinal …
[HTML][HTML] Epithelial barrier theory: the role of exposome, microbiome, and barrier function in allergic diseases
P Losol, M Sokolowska, YK Hwang… - Allergy, asthma & …, 2023 - ncbi.nlm.nih.gov
Allergic diseases are a major public health problem with increasing prevalence. These
immune-mediated diseases are characterized by defective epithelial barriers, which are …
immune-mediated diseases are characterized by defective epithelial barriers, which are …
Epithelial barrier hypothesis and the development of allergic and autoimmune diseases
The “epithelial barrier hypothesis” proposes that genetic predisposition to epithelial barrier
damage, exposure to various epithelial barrier–damaging agents and chronic periepithelial …
damage, exposure to various epithelial barrier–damaging agents and chronic periepithelial …
[HTML][HTML] The epithelial barrier: The gateway to allergic, autoimmune, and metabolic diseases and chronic neuropsychiatric conditions
Since the 1960 s, our health has been compromised by exposure to over 350,000 newly
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …
introduced toxic substances, contributing to the current pandemic in allergic, autoimmune …
Effect of altered human exposome on the skin and mucosal epithelial barrier integrity
Pollution in the world and exposure of humans and nature to toxic substances is
continuously worsening at a rapid pace. In the last 60 years, human and domestic animal …
continuously worsening at a rapid pace. In the last 60 years, human and domestic animal …
The epithelial barrier hypothesis proposes a comprehensive understanding of the origins of allergic and other chronic noncommunicable diseases
CA Akdis - Journal of Allergy and Clinical Immunology, 2022 - jacionline.org
A steep increase in the prevalence of many chronic noncommunicable diseases occurred
during the last 60 years, bringing them to a pandemic size. 1 Our research and efforts to …
during the last 60 years, bringing them to a pandemic size. 1 Our research and efforts to …
Dysregulation of the epithelial barrier by environmental and other exogenous factors
The “epithelial barrier hypothesis” proposes that the exposure to various epithelial barrier–
damaging agents linked to industrialization and urbanization underlies the increase in …
damaging agents linked to industrialization and urbanization underlies the increase in …