Mitochondria are essential for the activity, function and viability of eukaryotic cells and
mitochondrial dysfunction is involved in the pathogenesis of acute kidney injury (AKI) and …

Mitochondria are energy-producing organelles that not only satisfy the high metabolic
demands of the kidney but sense and respond to kidney injury-induced oxidative stress and …

The kidney is a vital organ that demands an extraordinary amount of energy to actively
maintain the body's metabolism, plasma hemodynamics, electrolytes and water …

Mitochondria are heterogeneous and highly dynamic organelles, playing critical roles in
adenosine triphosphate (ATP) synthesis, metabolic modulation, reactive oxygen species …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected conditions,
and CKD is projected to become the fifth leading global cause of death by 2040. New …

Abstract The kidneys compose approximately 0.5% of the body mass but consume about
10% of the oxygen in cellular respiration. This discordance is due to the high energy …

Acute kidney injury (AKI) is a common clinical entity that is associated with high mortality and
morbidity. It is a risk factor for the development and progression of chronic kidney disease …

The kidney contains many mitochondria that generate ATP to provide energy for cellular
processes. Oxidative stress injury can be caused by impaired mitochondria with excessive …

Acute kidney injury (AKI) is a common clinical disorder associated with decline in renal
function because of ischemic and nephrotoxic insults. The pathophysiology of AKI involves …

Mitochondrial dysfunction has gained recognition as a contributing factor in many diseases.
The kidney is a kind of organ with high energy demand, rich in mitochondria. As such …