Anti-tumor effects of pigment epithelium-derived factor (PEDF): implication for cancer therapy. A mini-review
L Belkacemi, SX Zhang - Journal of Experimental & Clinical Cancer …, 2016 - Springer
Pigment epithelium-derived factor (PEDF) is a secreted glycoprotein and a non-inhibitory
member of the serine protease inhibitor (serpin) family. It is widely expressed in human fetal …
member of the serine protease inhibitor (serpin) family. It is widely expressed in human fetal …
The effects of PEDF on cancer biology: mechanisms of action and therapeutic potential
SP Becerra, V Notario - Nature Reviews Cancer, 2013 - nature.com
The potent actions of pigment epithelium-derived factor (PEDF) on tumour-associated cells,
and its extracellular localization and secretion, stimulated research on this multifunctional …
and its extracellular localization and secretion, stimulated research on this multifunctional …
The role of PEDF in tumor growth and metastasis
D Hoshina, R Abe, SI Yamagishi… - Current molecular …, 2010 - ingentaconnect.com
Pigment epithelium-derived factor (PEDF), one of the non-inhibitory serpines, is widely
expressed throughout the body. Although PEDF was initially identified as a neuronal …
expressed throughout the body. Although PEDF was initially identified as a neuronal …
In vitro and in vivo biological activity of PEDF against a range of tumors
ML Broadhead, CR Dass… - Expert opinion on …, 2009 - Taylor & Francis
Background: Pigment epithelium-derived factor (PEDF) is an emerging anti-cancer agent
that targets both tumor tissue and its supporting vasculature. These direct and indirect effects …
that targets both tumor tissue and its supporting vasculature. These direct and indirect effects …
Pigment epithelium-derived factor: a multimodal tumor inhibitor
ETH Ek, CR Dass, PFM Choong - Molecular cancer therapeutics, 2006 - AACR
Pigment epithelium-derived factor (PEDF), a noninhibitory member of the serine protease
inhibitor (serpin) family, is a well-known potent endogenous inhibitor of angiogenesis. It has …
inhibitor (serpin) family, is a well-known potent endogenous inhibitor of angiogenesis. It has …
Therapeutic potential of pigment epithelium-derived factor in cancer
S Yamagishi, Y Koga, A Sotokawauchi… - Current …, 2019 - ingentaconnect.com
Pigment epithelium-derived factor (PEDF) is one of the serine protease inhibitors with
multifunctional properties, which is produced by various types of organs and tissues. There …
multifunctional properties, which is produced by various types of organs and tissues. There …
The increasing role of pigment epithelium-derived factor in metastasis: From biological importance to a promising target
R Abooshahab, H Al-Salami, CR Dass - Biochemical Pharmacology, 2021 - Elsevier
Pigment epithelium-derived factor (PEDF) is a non-inhibitory member of the serpin (serine
protease inhibitor) family and is a well-known potent anti-tumor factor in a variety of cancers …
protease inhibitor) family and is a well-known potent anti-tumor factor in a variety of cancers …
PEDF: a potential molecular therapeutic target with multiple anti-cancer activities
ETH Ek, CR Dass, PFM Choong - Trends in molecular medicine, 2006 - cell.com
Pigment epithelium-derived factor (PEDF) is an endogenously produced protein that is
widely expressed throughout the human body, and exhibits multiple and varied biological …
widely expressed throughout the human body, and exhibits multiple and varied biological …
Pigment epithelium-derived factor as a multifunctional antitumor factor
NI Fernández-García, OV Volpert, B Jimenez - Journal of Molecular …, 2007 - Springer
The design of new therapeutic strategies for cancer treatment is based on the combination of
drugs directed against different tumor compartments, including the tumor cells themselves …
drugs directed against different tumor compartments, including the tumor cells themselves …
Identification of Pigment Epithelium‐Derived Factor Protein Forms with Distinct Activities on Tumor Cell Lines
P Subramanian, M Deshpande… - BioMed Research …, 2012 - Wiley Online Library
Purpose. Pigment epithelium‐derived factor (PEDF) is a multifunctional serpin. The purpose
of this study is to identify PEDF protein forms and investigate their biological activities on …
of this study is to identify PEDF protein forms and investigate their biological activities on …