OBJECTIVE: Uric acid (UA) levels are frequently increased in patients with heart failure (HF),
and may be an indicator of a poor prognosis and an innovative target for treatment. We …

BACKGROUND: Previous studies have not extensively examined the association of
hyperuricemia and adverse outcomes in systolic heart failure (HF) in relation to xanthine …

STUDY OBJECTIVE: The aim of this study was to explore the prognostic role of serum uric
acid (UA) measurement in the hospital and long-term mortality assessment in subjects with …

Objective: To examine whether allopurinol is associated with any alteration in mortality and
hospitalisations in patients with chronic heart failure (CHF). This hypothesis is based on …

BACKGROUND: In severe chronic heart failure (CHF) elevated serum levels of uric acid
(UA) predict poor survival. This study investigates whether hyperuricaemia (defined as …

Background The serum level of uric acid (UA) is a well-known prognostic factor for heart
failure (HF) patients. However, the prognostic impact of hyperuricemia and the factors that …

There is a need for a cost-effective prognostic biomarker in heart failure (HF). Substantial
evidence suggests that uric acid (UA) is an independent marker for adverse prognosis in …

ABSTRACT Background and Aim: Increased xanthine oxidase (XO) activity may contribute
to heart failure pathophysiology. This study evaluated whether a XO inhibitor, allopurinol …

Background—Serum uric acid (UA) could be a valid prognostic marker and useful for
metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF) …

We investigated the clinical profiles associated with serum uric acid (sUA) levels in a large
cohort of patients hospitalized for worsening chronic heart failure with ejection fraction …