Hyperforin (HPF), the main component responsible for the antidepressant action of
Hypericum perforatum, displays additional beneficial properties including anti-inflammatory …

Hyperforin (HPF) is an acylphloroglucinol compound found abundantly in Hypericum
perforatum extract which exhibits antidepressant, anti-inflammatory, antimicrobial, and …

Breast cancer has been recorded as a frequent malignant cancer. The side effects of current
chemotherapy drugs are still a severe problem. Hence, naturally occurring phytochemicals …

The aim of the present study was to investigate the antitumor effect and mechanism of action
of hyperforin in hepatocellular carcinoma (HCC) SK-Hep1 cells in vitro. Cells were treated …

Background The natural phloroglucinol hyperforin HF displays anti-inflammatory and anti-
tumoral properties of potential pharmacological interest. Acute myeloid leukemia (AML) cells …

In this paper we review the mechanisms of the antitumor effects of Hypericum perforatum
L.(St. John's wort, SJW) and its main active component hyperforin (HPF). SJW extract is …

Hyperforin is a prenylated phloroglucinol present in the medicinal plant St John's wort
(Hypericum perforatum). The compound has many biological properties, including …

Hyperforin is an abundant phloroglucinol-type constituent isolated from the extract of the
flowering upper portion of the plant Hypericum perforatum L. The dicyclohexylammonium …

Extracts of the plant St John's wort, Hyperforin perforatum L., have been used for centuries in
traditional medicine, notably for the treatment of depression. One of their main lipophilic …

Glioblastoma is the most common primary brain tumor with poor survival rate and without
effective treatment strategy. Notably, amplification and active mutation of epidermal growth …