Aging is consistently reported as the most important independent risk factor for
neurodegenerative diseases. As life expectancy has significantly increased during the last …

Exosomes are small membranous entities of endocytic origin. Their production by a wide
variety of cells in eukaryotes implicates their roles in the execution of essential processes …

Abstract Alzheimer's disease (AD), manifested by memory loss and a decline in cognitive
functions, is the most prevalent neurodegenerative disease accounting for 60–80% of …

Exosomes are extracellular nanovesicles (30–100 nm) generated from endosomal
membranes and known to be released by all cell lineages of the Central Nervous System …

Alzheimer's disease (AD) is a neurodegenerative disease that mainly occurs in old age and
involves progressive cognitive impairment. AD has become a major global issue for public …

Intercellular communication between neurons and their surrounding cells occurs through the
secretion of soluble molecules or release of vesicles such as exosomes into the extracellular …

Extracellular vesicles (EVs) are nano-sized membrane-enclosed particles released by cells
that participate in intercellular communication through the transfer of biologic material. EVs …

Alzheimer's disease (AD) is characterized by a series of interacting pathophysiological
cascades, including the aggregation of β-amyloid plaques and the formation of …

Growing evidence indicates that small extracellular vesicles, called exosomes, are
prominent mediators of neurodegenerative diseases such as prion, Alzheimer's and …

Exosomes are potent mediators of physiological and pathological processes. In Alzheimer's
disease and inflammatory disorders, due to exosomes' distinctive ability to cross the blood …