Despite the fact that an amorphous solid dispersion (ASD)-coated pellet formulation offers
potential advantages regarding the minimization of physical stability issues, there is still a …

In spite of the fact that spray drying is widely applied for the formulation of amorphous solid
dispersions (ASDs), the influence of the solvent on the physical properties of the ASDs is still …

In spite of the large research efforts in the past two decades, it is still difficult, if possible at all,
to predict what manufacturing technology will lead to the best amorphous solid dispersions …

Purpose To present a new screening methodology intended to be used in the early
development of spray-dried amorphous solid dispersions. Methods A model that combines …

Inhibiting surface crystallization is an interesting strategy to enhance the physical stability of
amorphous solid dispersions (ASDs), still preserving high drug loads. The aim of this study …

The formulation of oral amorphous solid dispersions (ASD) includes the use of excipients to
improve physical stability and enhance bioavailability. Combinations of excipients (polymers …

The aim of this paper was to investigate whether a surface coating technique could be
developed that can predict the phase behavior of amorphous solid dispersions (ASDs) …

Amorphous solid dispersions (ASDs) enable formulations to improve the solubility of poorly
soluble active pharmaceutical ingredients (APIs). The amorphous state is reached through …

Spray drying is one of the most frequently used solvent-based processes for manufacturing
amorphous solid dispersions (ASDs). However, the resulting fine powders usually require …

Bead coating or fluid-bed coating serves as an auspicious solvent-based amorphous solid
dispersion (ASD) manufacturing technique in respect of minimization of potential physical …