National Institutes of Health–sponsored Clinical Islet Transplantation Consortium phase 3 trial: manufacture of a complex cellular product at eight processing facilities
C Ricordi, JS Goldstein, AN Balamurugan, GL Szot… - Diabetes, 2016 - Am Diabetes Assoc
Eight manufacturing facilities participating in the National Institutes of Health–sponsored
Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a …
Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a …
[PDF][PDF] NIH-sponsored clinical islet transplantation consortium phase 3 trial: manufacture of a complex cellular product at eight processing facilities
C Ricordi, JS Goldstein, AN Balamurugan, GL Szot… - Diabetes, 2016 - researchgate.net
Transplantation (CIT) Consortium jointly developed and implemented a harmonized process
for manufacture of the allogeneic Purified Human Pancreatic Islet (PHPI) product evaluated …
for manufacture of the allogeneic Purified Human Pancreatic Islet (PHPI) product evaluated …
[HTML][HTML] Shipment of human islets for transplantation
The use of regional human islet cell processing centers (ICPC) supporting distant clinical
islet transplantation programs (CITP) has proven successful in recent clinical trials …
islet transplantation programs (CITP) has proven successful in recent clinical trials …
Human pancreatic islets and diabetes research
JS Kaddis, BJ Olack, J Sowinski, J Cravens… - Jama, 2009 - jamanetwork.com
Human islet research is crucial to understanding the cellular biology of the pancreas in
developing therapeutic options for diabetes patients and in attempting to prevent the …
developing therapeutic options for diabetes patients and in attempting to prevent the …
Future trends in islet cell transplantation
AMJ Shapiro, JRT Lakey - Diabetes technology & therapeutics, 2000 - liebertpub.com
THE RECENT DRAMATIC TRANSFORMATION in outcome of clinical islet transplantation
reported by our group has secured a future for this therapy in diabetes. 1, 2 The Islet …
reported by our group has secured a future for this therapy in diabetes. 1, 2 The Islet …
Quality control for clinical islet transplantation: organ procurement and preservation, the islet processing facility, isolation, and potency tests
T Yamamoto, A Horiguchi, M Ito, H Nagata… - Journal of hepato-biliary …, 2009 - Springer
Pancreatic islet transplantation has become one of the ideal treatments for patients with type
1 diabetes mellitus due to improvements in isolation techniques and immunosuppression …
1 diabetes mellitus due to improvements in isolation techniques and immunosuppression …
Improved human pancreatic islet isolation for a prospective cohort study of islet transplantation vs best medical therapy in type 1 diabetes mellitus
GL Warnock, RM Meloche, D Thompson… - Archives of …, 2005 - jamanetwork.com
Hypothesis A local multiorgan donor pancreas procurement program can provide a source
for optimized isolation of purified viable islets for transplantation into patients with type 1 …
for optimized isolation of purified viable islets for transplantation into patients with type 1 …
[HTML][HTML] Rescue purification maximizes the use of human islet preparations for transplantation
The relative inefficiency of the islet purification process may hamper obtaining enough islets
for transplantation even with adequate pre-purification counts. In this study, we determined …
for transplantation even with adequate pre-purification counts. In this study, we determined …
Characterization of islet preparations
Following the initial report in 2000 from Edmonton of insulin independence in the first seven
patients treated with a new protocol [171], nearly 500 patients with type 1 diabetes received …
patients treated with a new protocol [171], nearly 500 patients with type 1 diabetes received …
Efficacy of human islet isolation from the tail section of the pancreas for the possibility of living donor islet transplantation
S Matsumoto, K Tanaka, DM Strong, JA Reems - Transplantation, 2004 - journals.lww.com
Background. Islet transplantation is on the rise for the treatment of type 1 diabetes. Apparent
donor shortages could be alleviated through use of living donor pancreata. A critical issue …
donor shortages could be alleviated through use of living donor pancreata. A critical issue …