Importance In the US and the United Kingdom, cocaine use is the second leading cause of
illicit drug overdose death. Psychosocial treatments for cocaine use disorder are limited, and …

Background Currently, there are no accepted FDA-approved pharmacotherapies for cocaine
use disorder, though numerous medications have been tested in clinical trials. We …

Aims Cocaine dependence is a common and serious condition, associated with severe
medical, psychological and social problems, including the spread of infectious diseases …

Background Cocaine misuse is a disorder for which no pharmacological treatment of proven
efficacy exists. Advances in neurobiology could guide future medication development …

Antipsychotic medications for cocaine dependence - Indave, BI - 2016 | Cochrane Library Skip
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Background Cocaine dependence is a severe disorder for which no medication has been
approved. Like opioids for heroin dependence, replacement therapy with psychostimulants …

Cocaine use disorder is a persistent public health problem for which no widely effective
medications exist. Self-administration procedures, which have shown good predictive …

Background Cocaine dependence is an increasingly prevalent disorder for which no
medication is approved yet. Likewise opioid for heroin dependence, replacement therapy …

Background Clinical guidelines recommend psychosocial interventions for cocaine and/or
amphetamine addiction as first-line treatment, but it is still unclear which intervention, if any …

Cocaine is a stimulant that leads to the rapid accumulation of catecholamines and serotonin
in the brain due to prevention of their re-uptake into the neuron that released the …