Identification of the diagnostic genes and immune cell infiltration characteristics of gastric cancer using bioinformatics analysis and machine learning

R Xie, L Liu, X Lu, C He, G Li - Frontiers in Genetics, 2023 - frontiersin.org
Background: Finding reliable diagnostic markers for gastric cancer (GC) is important. This
work uses machine learning (ML) to identify GC diagnostic genes and investigate their …

[HTML][HTML] Bioinformatic analysis of hub markers and immune cell infiltration characteristics of gastric cancer

C Li, T Yang, Y Yuan, R Wen, H Yu - Frontiers in Immunology, 2023 - frontiersin.org
Background Gastric cancer (GC) is the fifth most common cancer and the second leading
cause of cancer-related deaths worldwide. Due to the lack of specific markers, the early …

Identification of Key Genes Associated with Tumor Microenvironment Infiltration and Survival in Gastric Adenocarcinoma via Bioinformatics Analysis

G Konstantis, G Tsaousi, C Pourzitaki… - Cancers, 2024 - mdpi.com
Simple Summary This study aimed to pinpoint immune-related genes that show heightened
activity in cancerous tissue and explore their correlation with cell infiltration in the tumor …

Identification of a novel 10 immune‐related genes signature as a prognostic biomarker panel for gastric cancer

T Chen, C Yang, R Dou, B Xiong - Cancer Medicine, 2021 - Wiley Online Library
Background Emerging evidence indicates that immune infiltrating cells in tumor
microenvironment (TME) correlates with the development and progression of gastric cancer …

[HTML][HTML] Identification and validation of immune cells and hub genes in gastric cancer microenvironment

H Wang, J Rong, Q Zhao, C Song, R Zhao, S Chen… - Disease …, 2022 - hindawi.com
Gastric cancer (GC) is the most common malignant tumor in the digestive system, traditional
radiotherapy and chemotherapy are not effective for some patients. The research progress …

[HTML][HTML] Screening and identification of key biomarkers of gastric cancer: three genes jointly predict gastric cancer

M Shan, L Meng, P Guo, Y Zhang, D Kong… - Frontiers in oncology, 2021 - frontiersin.org
Key words: Gastric cancer, gene expression profiling, bioinformatics analysis, weighted
gene co-expression network analysis, neural network model. Gastric cancer (GC) is the fifth …

[HTML][HTML] Identification of key genes in gastric cancer by bioinformatics analysis

X Chong, R Peng, Y Sun, L Zhang… - BioMed Research …, 2020 - hindawi.com
Gastric cancer (GC) is one of the most common malignancies of the digestive system with
few genetic markers for its early detection and prevention. In this study, differentially …

Immune-related genes and their determined immune cell microenvironment to predict the prognosis of gastric adenocarcinoma

N Xia, L Xia, WF Zhang, FX Zhou - Zhonghua yi xue za zhi, 2022 - europepmc.org
Objective: Through bioinformatics analysis to screen key immune-related genes (IRGs) and
cancer-related pathways in gastric adenocarcinoma (GAC) therapy, combining immune cell …

[HTML][HTML] Identification of molecular features correlating with tumor immunity in gastric cancer by multi-omics data analysis

Y He, X Wang - Annals of translational medicine, 2020 - ncbi.nlm.nih.gov
Background Although immunotherapy has achieved success in treating various refractory
malignancies including gastric cancers (GCs) with DNA mismatch repair deficiency, only a …

Key genes associated with prognosis and tumor infiltrating immune cells in gastric cancer patients identified by cross-database analysis

T Zhang, BF Wang, XY Wang, L Xiang… - Cancer Biotherapy & …, 2020 - liebertpub.com
Background: The molecular mechanisms underlying gastric cancer (GC) progression are
unclear. The authors examined key genes associated with the prognosis and tumor …