OBJECTIVE To evaluate the literature associating the risk of fracture during antidepressant
therapy. DATA SOURCES Literature was identified via MEDLINE (1970–August 2008) using …

Antidepressants come in a variety of types, the main types being tricyclic antidepressants
(TCAs), selective serotonin reuptake inhibitors (SSRIs) and the group of other …

We examined variations in fracture rates among patients initiated on antidepressant drug
treatment as identified from Medicare data in two US states and assessed whether the …

Background: Fractures related to osteoporosis and falling constitute a major health problem
in the elderly population. Exposure to antidepressants is associated with an increased risk of …

Previous studies have reported inconsistent findings regarding the association between the
use of selective serotonin reuptake inhibitors (SSRIs) and the risk of fracture. We identified …

Studies on use of selective serotonin reuptake inhibitors (SSRIs) and risk of fracture have
yielded inconsistent results. This meta-analysis, which pooled results from 13 qualifying …

Background Antidepressants may increase the risk of fractures by disrupting sensory-motor
function, thereby increasing the risk of falls, and by decreasing bone mineral density and …

Objective To evaluate the association between selective serotonin reuptake inhibitor (SSRI)
and selective serotonin and norepinephrine reuptake inhibitor (SNRI) use and risk of …

Background Depression and osteoporotic fractures are common ailments among elderly
persons. Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment …

This is the first study to investigate the association between the use of selective serotonin
reuptake inhibitor (SSRI)/serotonin–norepinephrine reuptake inhibitor (SNRI) and the risk of …