Nanobiotechnology-assisted therapies to manage brain cancer in personalized manner

M Nehra, UT Uthappa, V Kumar, R Kumar… - Journal of Controlled …, 2021 - Elsevier
There are numerous investigated factors that limit brain cancer treatment efficacy such as
ability of prescribed therapy to cross the blood-brain barrier (BBB), tumor specific delivery of …

Targeting to brain tumor: Nanocarrier-based drug delivery platforms, opportunities, and challenges

LA Kumar, G Pattnaik, BS Satapathy… - Journal of Pharmacy …, 2021 - journals.lww.com
Cancer is a class of disorder characterized by anomalous growth of cells escalating in an
uncontrolled way. Among all the cancers, treatment of cancerous brain tumors has been a …

Smart nanoformulations for brain cancer theranostics: challenges and promises

F Ahmad, R Varghese, S Panda, S Ramamoorthy… - Cancers, 2022 - mdpi.com
Simple Summary Brain metastases are amongst the most invasive and lethal cancers. Yet,
effective methods for their diagnosis and therapy have remained elusive. While several …

The exciting potential of nanotherapy in brain-tumor targeted drug delivery approaches

V Agrahari - Neural Regeneration Research, 2017 - journals.lww.com
Delivering therapeutics to the central nervous system (CNS) and brain-tumor has been a
major challenge. The current standard treatment approaches for the brain-tumor comprise of …

Recent advances in drug delivery systems for targeting brain tumors

Y Zhao, P Yue, Y Peng, Y Sun, X Chen, Z Zhao… - Drug delivery, 2023 - Taylor & Francis
Brain tumor accounts for about 1.6% of incidence and 2.5% of mortality of all tumors, and the
median survival for brain tumor patients is only about 20 months. The treatment for brain …

Drug delivery and targeting to brain tumors: Considerations for crossing the blood-brain barrier

Y Omidi, N Kianinejad, Y Kwon… - Expert Review of Clinical …, 2021 - Taylor & Francis
Introduction: The blood-brain barrier (BBB) selectively impedes the transportation of drug
molecules into the brain, which makes the drug delivery and targeting of brain tumors very …

Combinatorial therapeutic strategies for enhanced delivery of therapeutics to brain cancer cells through nanocarriers: current trends and future perspectives

X Wang, C Wu, S Liu, D Peng - Drug Delivery, 2022 - Taylor & Francis
Brain cancer is the most aggressive one among various cancers. It has a drastic impact on
people's lives because of the failure in treatment efficacy of the currently employed …

Multifunctional nanomedicine strategies to manage brain diseases

P Faria, C Pacheco, RP Moura, B Sarmento… - Drug Delivery and …, 2023 - Springer
Brain diseases represent a substantial social and economic burden, currently affecting one
in six individuals worldwide. Brain research has been focus of great attention in order to …

Advances in targeted drug delivery approaches for the central nervous system tumors: the inspiration of nanobiotechnology

J Meng, V Agrahari, I Youm - Journal of Neuroimmune Pharmacology, 2017 - Springer
At present, brain tumor is among the most challenging diseases to treat and the therapy is
limited by the lack of effective methods to deliver anticancer agents across the blood-brain …

Nanotechnology-enabled therapies improve blood-brain barrier challenges in brain tumor

Y Wenqi, W Lingxi, A Mehmood… - International Journal of …, 2023 - Taylor & Francis
The treatment of brain tumors has been predominantly hindered by the limited ability of
drugs to penetrate the blood-brain barrier. However, recent advancements in …