Multiexponential T2 relaxation time measurement in the central nervous system shows a
component that originates from water trapped between the lipid bilayers of myelin. This …

Multicomponent T2 relaxation imaging can be used to measure signal from water trapped
between myelin bilayers; the ratio of myelin water signal to total water is termed the myelin …

Myelin water imaging, a magnetic resonance imaging technique capable of resolving the
fraction of water molecules which are located between the layers of myelin, is a valuable tool …

Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content
has important implications for understanding brain plasticity and neurodegenerative …

Myelin water imaging (MWI) is an MRI imaging biomarker for myelin. This method can
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …

Quantitative assessment of the myelin water content in the brain can substantially improve
our understanding of white matter diseases such as multiple sclerosis. In this study, in vivo …

Purpose Myelin water fraction is conventionally measured from the T2 decay curve.
Recently, a steady‐state approach entitled multicomponent‐driven equilibrium single pulse …

Purpose The multi‐exponential T2 decay of the MRI signal from cerebral white matter can be
separated into short T2 components related to myelin water and long T2 components related …

Myelin water imaging (MWI) promises to be invaluable in understanding neurological
diseases like MS. However, a limitation of MWI is signal to noise ratio. Recently, a number of …

Damage to myelin is a key feature of multiple sclerosis (MS) pathology. Magnetic resonance
imaging (MRI) has revolutionized our ability to detect and monitor MS pathology in vivo …