Although it was originally believed that thyroid hormones enter target cells by passive
diffusion, it is now clear that cellular uptake is effected by carrier-mediated processes. Two …

The transport of [125I] thyroxine (T4) and [125I] triiodothyronine (T3) into liver was
investigated with a tissue sampling-portal vein injection technique in the anesthetized rat …

Thyroid hormone content of cerebrospinal fluid (CSF) pooled from euthyroid patients was
studied because of its possible relationship to brain T4 and T3 levels. The mean CSF total …

Transport of 3, 5-[3'-125I] triiodo-L-thyronine ([125I] T3) was studied in isolated rat liver
hepatocytes. T3 transport was temperature-sensitive, the initial velocity of uptake, at low …

Thyroid hormone action and metabolism are intracellular events that require transport of the
hormone across the plasma membrane. We tested the possible involvement of the …

Thyroid hormones orchestrate developmental processes and are among the most important
regulators of energy metabolism. Thyroid hormone actions are mostly, but not exclusively …

The transport of [l25I] T3., and [l25I] T4 through the brain capillary wall, ie the blood-brain
barrier, was studied in barbiturate-anesthetized rats using a tissue-sampling-carotid …

Thyroid hormone is important for development of various tissues, in particular brain, and for
regulation of metabolic processes throughout life. The follicular cells of the thyroid gland …

We used autoradiography to test the hypothesis that a major function of thyroid hormone-
binding proteins in plasma is to ensure uniform distribution of thyroid hormones among cells …

Thyroid hormones, being hydrophobic, were thought to enter target cell membranes by
passive diffusion. However, recent studies have documented the existence of numerous …