Patient-specific electromechanical models of the heart for the prediction of pacing acute effects in CRT: a preliminary clinical validation

M Sermesant, R Chabiniok, P Chinchapatnam… - Medical image …, 2012 - Elsevier
Cardiac resynchronisation therapy (CRT) is an effective treatment for patients with
congestive heart failure and a wide QRS complex. However, up to 30% of patients are non …

[HTML][HTML] A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data

AWC Lee, UC Nguyen, O Razeghi, J Gould… - Medical image …, 2019 - Elsevier
Abstract Background Cardiac Resynchronization Therapy (CRT) is one of the few effective
treatments for heart failure patients with ventricular dyssynchrony. The pacing location of the …

A computational approach to understanding the cardiac electromechanical activation sequence in the normal and failing heart, with translation to the clinical practice …

J Constantino, Y Hu, NA Trayanova - Progress in biophysics and molecular …, 2012 - Elsevier
Cardiac resynchronization therapy (CRT) is an established clinical treatment modality that
aims to recoordinate contraction of the heart in dyssynchrous heart failure (DHF) patients …

Patient-specific modeling of dyssynchronous heart failure: a case study

J Aguado-Sierra, A Krishnamurthy, C Villongco… - Progress in biophysics …, 2011 - Elsevier
The development and clinical use of patient-specific models of the heart is now a feasible
goal. Models have the potential to aid in diagnosis and support decision-making in clinical …

Impact of left ventricular lead position on the efficacy of cardiac resynchronisation therapy: a two-dimensional strain echocardiography study

M Becker, A Franke, OA Breithardt, C Ocklenburg… - Heart, 2007 - heart.bmj.com
Background: Definition of the optimal left ventricular (LV) lead position in cardiac
resynchronisation therapy (CRT) is desirable. Objective: To define the optimal LV lead …

Transfer learning from simulations on a reference anatomy for ECGI in personalized cardiac resynchronization therapy

S Giffard-Roisin, H Delingette, T Jackson… - IEEE Transactions …, 2018 - ieeexplore.ieee.org
Goal: Noninvasive cardiac electrophysiology (EP) model personalisation has raised interest
for instance in the scope of predicting EP cardiac resynchronization therapy (CRT) …

Noninvasive personalization of a cardiac electrophysiology model from body surface potential mapping

S Giffard-Roisin, T Jackson, L Fovargue… - IEEE Transactions …, 2016 - ieeexplore.ieee.org
Goal: We use noninvasive data (body surface potential mapping, BSPM) to personalize the
main parameters of a cardiac electrophysiological (EP) model for predicting the response to …

Length-dependent tension in the failing heart and the efficacy of cardiac resynchronization therapy

SA Niederer, G Plank, P Chinchapatnam… - Cardiovascular …, 2011 - academic.oup.com
Aims Cardiac resynchronization therapy (CRT) has emerged as one of the few effective and
safe treatments for heart failure. However, identifying patients that will benefit from CRT …

[HTML][HTML] Cardiac resynchronization: insight from experimental and computational models

RCP Kerckhoffs, J Lumens, K Vernooy… - Progress in biophysics …, 2008 - Elsevier
Cardiac resynchronization therapy (CRT) is a promising therapy for heart failure patients
with a conduction disturbance, such as left bundle branch block. The aim of CRT is to …

Three-dimensional mapping of optimal left ventricular pacing site for cardiac resynchronization

RH Helm, M Byrne, PA Helm, SK Daya, NF Osman… - Circulation, 2007 - Am Heart Assoc
Background—The efficacy of cardiac resynchronization therapy (CRT) depends on
placement of the left ventricular lead within the late-activated territory. The geographic extent …