Neural basis of operant behaviors maintained on the differential-reinforcement-of-low-rate (DRL) schedule in rodents

RM Liao, T Pattij - Brain Research Bulletin, 2022 - Elsevier
Various schedules of reinforcement have long been used in experimental psychology to
establish and maintain operant behaviors. These reinforcement contingencies have also …

Regional differences in dopamine receptor blockade affect timing impulsivity that is altered by d-amphetamine on differential reinforcement of low-rate responding …

RK Cheng, RM Liao - Behavioural Brain Research, 2017 - Elsevier
The ability to control when to start an action and when to stop is crucial in human and animal
behavior. A failure to suppress premature behavior or to carry out an action in a timely …

[PDF][PDF] Acute effects of d-amphetamine on the differential reinforcement of low-rate (DRL) schedule behavior in the rat: comparison with selective dopamine receptor …

R Liao, R Cheng - Chinese Journal of Physiology, 2005 - researchgate.net
Amphetamine and it analogs have been shown to affect operant behavior maintained on the
differential reinforcement of a low-rate (DRL) schedule. The aim of the present study was to …

Timing and space usage are disrupted by amphetamine in rats maintained on DRL 24-s and DRL 72-s schedules of reinforcement

SC Fowler, J Pinkston, E Vorontsova - Psychopharmacology, 2009 - Springer
Rationale A differential-reinforcement-of-low-rate schedule (DRL) delivers reinforcement
only when the interresponse time (IRT) exceeds a fixed time interval, thereby shaping rats to …

Concurrent progressive-ratio schedules: Built-in controls in the study of delayed reward efficacy

DP Jarmolowicz, JL Hudnall - Journal of Neuroscience Methods, 2014 - Elsevier
Background Delayed rewards maintain lower rates of operant responding than immediate
rewards, and when given a choice between immediate and delayed rewards, individuals …

Differential-Reinforcement-of-Low-Rate Behavior in Rodents as a Screen for Antidepressant Efficacy

LM Lueptow, JM O'Donnell - Mood and Anxiety Related Phenotypes in …, 2011 - Springer
Abstract Differential-reinforcement-of-low-rate (DRL) is an operant conditioning schedule
that requires behavioral inhibition for a given length of time, known as the interresponse time …

Investigating temporal memory strength and time-based impulse control using the DRL task

RK Cheng, RM Liao - Timing & Time Perception, 2022 - brill.com
Differential reinforcement of low rate (DRL) responding is a schedule-controlled behavior
sometimes used in timing research, but also received critics of not providing a pure measure …

Antidepressant effects assessed using behavior maintained under a differential-reinforcement-of-low-rate (DRL) operant schedule

JM O'Donnell, GJ Marek, LS Seiden - Neuroscience & Biobehavioral …, 2005 - Elsevier
Behavior maintained under a differential-reinforcement-of-low-rate (DRL) 72-s operant
schedule, which reinforces responses with interresponse times greater than 72s, exhibits a …

Novel reinforcement learning paradigm based on response patterning under interval schedules of reinforcement

C Schifani, I Sukhanov, M Dorofeikova… - Behavioural Brain …, 2017 - Elsevier
There is a need to develop cognitive tasks that address valid neuropsychological constructs
implicated in disease mechanisms and can be used in animals and humans to guide novel …

The effect of delayed reinforcement on DRL performance

D Meltzer, JA Brahlek - Psychonomic Science, 1967 - Springer
Stable DRL performance of four rats was studied under conditions of delayed reinforcement.
A DRL 20 sec requirement remained in effect across all sessions while the delay of …