Regulatory T (Treg) cells underlie multiple autoimmune disorders and potentialize an anti-
inflammation treatment with adoptive cell therapy. However, systemic delivery of cellular …

Psoriasis is a chronic, autoimmune, and non-communicable skin disease with a worldwide
prevalence rate of 2–3%, creating an economic burden on global health. Some significant …

The skin is an absorptive organ, targeted in the transdermal delivery system. The
microneedle method is an updated approach to deliver compounds through the skin in an …

Psoriasis is an inflammatory skin disease. Microneedle (MN) patches can improve psoriasis
treatment outcomes by increasing local drug content in the skin. As psoriasis frequently …

Objective Adoptive Treg cell therapy has great potential to treat autoimmune disease.
Currently, very little is known about how these cells impact inflamed tissues. This study was …

Purpose Oxidative stress, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-
κB) and adenosine signaling are factors associated with psoriatic inflammation. Topical …

Cell-based therapies for autoimmune diseases have gained significant traction, with several
approaches centered around the regulatory T (Treg) cell─ a well-known …

Forkhead box P3–expressing regulatory T (Treg) cells are essential for self-tolerance, with
an emerging role in tissue repair and regeneration. Their ability to traffic to tissue and …

The goal of immunotherapy against autoimmunity is to block pathogenic inflammation
without impairing immunity against infections and tumours. Regulatory T-cells (Tregs) play a …

Engineered regulatory T (Treg) cells have emerged as precision therapeutics aimed at
inducing immune tolerance while reducing the risks associated with generalized …