[PDF][PDF] Hypercoagulable states: an algorithmic approach to laboratory testing and update on monitoring of direct oral anticoagulants

MO Nakashima, HJ Rogers - Blood research, 2014 - synapse.koreamed.org
Hypercoagulability can result from a variety of inherited and, more commonly, acquired
conditions. Testing for the underlying cause of thrombosis in a patient is complicated both by …

[HTML][HTML] Interference of direct oral anticoagulants in haemostasis assays: high potential for diagnostic false positives and false negatives

EJ Favaloro, G Lippi - Blood Transfusion, 2017 - ncbi.nlm.nih.gov
Many patients have a variety of prothrombotic risk factors or conditions, and these patients
are often given anticoagulant/antithrombotic treatment. Such treatments for thromboembolic …

Hypercoagulability: too many tests, too much conflicting data

KA Bauer, FR Rosendaal, JA Heit - ASH Education Program …, 2002 - ashpublications.org
It is now possible to identify hereditary and acquired risk factors in a substantial percentage
of patients presenting with a venous thrombotic event. The clinician is faced with an ever …

Laboratory evaluation of hypercoagulability

B Khor, EM Van Cott - Clinics in laboratory medicine, 2009 - Elsevier
This discussion considers several important hypercoagulable states that predispose patients
to venous, and in some instances, arterial thrombosis, focusing on activated protein C …

[HTML][HTML] Global assays of hemostasis in the diagnostics of hypercoagulation and evaluation of thrombosis risk

EN Lipets, FI Ataullakhanov - Thrombosis journal, 2015 - Springer
Thrombosis is a deadly malfunctioning of the hemostatic system occurring in numerous
conditions and states, from surgery and pregnancy to cancer, sepsis and infarction. Despite …

[HTML][HTML] International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of direct oral anticoagulants

RC Gosselin, DM Adcock, SM Bates… - Thrombosis and …, 2018 - thieme-connect.com
This guidance document was prepared on behalf of the International Council for
Standardization in Haematology (ICSH) for providing haemostasis-related guidance …

[HTML][HTML] The laboratory's 2015 perspective on direct oral anticoagulant testing

RC Gosselin, DM Adcock - Journal of Thrombosis and Haemostasis, 2016 - Elsevier
The introduction of direct oral anticoagulant (DOAC) therapy into clinical use in the past 5
years has had significant impact on the clinical laboratory. Clinicians' desire to determine …

The new oral anticoagulants and the future of haemostasis laboratory testing

EJ Favaloro, G Lippi - Biochemia Medica, 2012 - hrcak.srce.hr
Sažetak The tests currently employed within most haemostasis laboratories to monitor
anticoagulant therapy largely comprise the prothrombin time (PT)/International Normalised …

Practical guidance on the use of laboratory testing in the management of bleeding in patients receiving direct oral anticoagulants

H Ten Cate, YMC Henskens… - Vascular health and risk …, 2017 - Taylor & Francis
Direct oral anticoagulants (DOACs) have demonstrated a favorable benefit–risk profile in
several thromboembolic disorders and are increasingly used in routine clinical practice. A …

Coagulation assays and anticoagulant monitoring

DM Funk - Hematology 2010, the American Society of …, 2012 - ashpublications.org
Anticoagulant therapy, including conventional agents and a variety of new oral, fast-acting
drugs, is prescribed for millions of patients annually. Each anticoagulant varies in its effect …