The role of ANO6/TMEM16F phospholipid scramblase in SARS-CoV-2 infection
심주리 - 2023 - ir.ymlib.yonsei.ac.kr
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, is enveloped virus and has the Spike (S) glycoprotein on the virion envelope …
COVID-19, is enveloped virus and has the Spike (S) glycoprotein on the virion envelope …
[HTML][HTML] Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition
JR Sim, DH Shin, PG Park, SH Park, JY Bae, Y Lee… - Cell reports, 2022 - cell.com
As an enveloped virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
delivers its viral genome into host cells via fusion of the viral and cell membranes. Here, we …
delivers its viral genome into host cells via fusion of the viral and cell membranes. Here, we …
[HTML][HTML] SARS-CoV-2 ion channel ORF3a enables TMEM16F-dependent phosphatidylserine externalization to augment procoagulant activity of the tenase and …
JG Ludington, SA Ansari, AA Schmaier, K Enjyoji… - Blood, 2021 - Elsevier
Severe SARS-CoV-2 infection is complicated by dysregulation of the blood coagulation
system and high rates of thrombosis, but virus-intrinsic mechanisms underlying this …
system and high rates of thrombosis, but virus-intrinsic mechanisms underlying this …
[HTML][HTML] Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic. Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for SARS-CoV-2 …
pandemic. Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for SARS-CoV-2 …
[HTML][HTML] SARS-CoV-2 hijacks macropinocytosis to facilitate its entry and promote viral spike–mediated cell-to-cell fusion
YY Zhang, R Liang, SJ Wang, ZW Ye, TY Wang… - Journal of Biological …, 2022 - ASBMB
Revealing the mechanisms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) entry and cell-to-cell spread might provide insights for understanding the underlying …
2) entry and cell-to-cell spread might provide insights for understanding the underlying …
Calpain-2 mediates SARS-CoV-2 entry via regulating ACE2 levels
Q Zeng, A Antia, LA Casorla-Perez, M Puray-Chavez… - Mbio, 2024 - Am Soc Microbiol
Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, much effort has
been dedicated to identifying effective antivirals against severe acute respiratory syndrome …
been dedicated to identifying effective antivirals against severe acute respiratory syndrome …
[HTML][HTML] SKI-1/S1P facilitates SARS-CoV-2 spike induced cell-to-cell fusion via activation of SREBP-2 and metalloproteases, whereas PCSK9 enhances the …
R Essalmani, U Andréo, A Evagelidis, M Le Dévéhat… - Viruses, 2023 - mdpi.com
Proprotein convertases activate various envelope glycoproteins and participate in cellular
entry of many viruses. We recently showed that the convertase furin is critical for the …
entry of many viruses. We recently showed that the convertase furin is critical for the …
Metalloproteinase-dependent and TMPRSS2-independent cell surface entry pathway of SARS-CoV-2 requires the furin cleavage site and the S2 domain of spike …
M Yamamoto, J Gohda, A Kobayashi, K Tomita… - Mbio, 2022 - Am Soc Microbiol
The ongoing global vaccination program to prevent SARS-CoV-2 infection, the causative
agent of COVID-19, has had significant success. However, recently, virus variants that can …
agent of COVID-19, has had significant success. However, recently, virus variants that can …
[HTML][HTML] NSP16 promotes the expression of TMPRSS2 to enhance SARS-CoV-2 cell entry
T Han, J Lei, Y Liu, Y Wang, W Xun, Q Hu… - Genes & …, 2023 - ncbi.nlm.nih.gov
Since the end of 2019, COVID-19 has caused worldwide pandemic. SARS-CoV-2, the culprit
of this epidemic, binds to the host receptor Angiotensin converting enzyme 2 (ACE2) using …
of this epidemic, binds to the host receptor Angiotensin converting enzyme 2 (ACE2) using …
TMEM106B-mediated SARS-CoV-2 infection allows for robust ACE2-independent infection in vitro but not in vivo
Angiotensin converting enzyme 2 (ACE2) serves as the primary entry receptor for severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, ACE2-independent …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, ACE2-independent …