The objective of this study was to test the hypothesis that administration of l-arginine, a
substrate for nitric oxide synthase, restores acetylcholine-induced dilatation of the basilar …

We evaluated the response of pial arterioles to l-arginine in anesthetized normotensive rats
and spontaneously hypertensive rats equipped with a closed cranial window. Topical …

Background and Purpose Nitric oxide is an important regulator of vascular tone and may
also be implicated in the modulation of vascular growth and structure. This study presents …

The goal of this study was to test the hypothesis that administration of L-arginine, a substrate
for the synthesis of nitric oxide, restores endothelium-dependent dilatation of the basilar …

This study examined both basal and agonist-stimulated effects of nitric oxide in rings of
thoracic aorta and carotid artery from 12-week-old stroke-prone spontaneously hypertensive …

Previous studies have suggested that nitric oxide (NO) may be a major endothelium-derived
relaxing factor in peripheral blood vessels. This study tested the hypotheses that 1) …

Objective To investigate the influence of hypertension and ageing on the in vivo effect of
acetylcholine on blood pressure and regional vascular conductance and the inhibitory effect …

Background It is unknown whether β-adrenoceptor-mediated vasodilatation is altered in
early hypertension and whether it can be modulated by l-arginine. Methods and design We …

Hypertension-associated alterations of the nitric oxide (NO) pathway were analyzed in
middle cerebral arteries (MCA) from normotensive (WKY) and hypertensive (SHR) rats. The …

This study was designed to investigate the effects of L-arginine (the substrate of endothelium-
derived nitric oxide) in human forearm vessels. We examined whether intra-arterial infusion …