Physiological effect of ghrelin on body systems

Y Akalu, MD Molla, G Dessie… - International journal of …, 2020 - Wiley Online Library
Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of
physiological effects. In this review, we found/confirmed that ghrelin has effect on all body …

Ghrelin: a new peptide regulating the neurohormonal system, energy homeostasis and glucose metabolism

P Pusztai, B Sarman, E Ruzicska, J Toke… - Diabetes/metabolism …, 2008 - Wiley Online Library
Identification of ghrelin started with the discovery of growth hormone secretagogues,
continued with the description of ghrelin receptors and ended with the elucidation of the …

Ghrelin and its biochemical functions

S Aydın, Y Özkan, E Caylak, S Aydın - 2006 - cabidigitallibrary.org
Ghrelin (also known as hunger hormone) is an orexigenic peptide hormone composed of 28
amino acid residues. It was discovered by Japanese scientists in 1999. After its discovery, it …

[HTML][HTML] Interrelationships between ghrelin, insulin and glucose homeostasis: physiological relevance

F Chabot, A Caron, M Laplante… - World journal of …, 2014 - ncbi.nlm.nih.gov
Ghrelin is a 28 amino acid peptide mainly derived from the oxyntic gland of the stomach.
Both acylated (AG) and unacylated (UAG) forms of ghrelin are found in the circulation …

[HTML][HTML] Ghrelin: ghrelin as a regulatory Peptide in growth hormone secretion

N Khatib, S Gaidhane, AM Gaidhane… - Journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Background: Ghrelin is a type of growth hormone (GH) secretagogue that stimulates the
release of GH. It is a first hormone linking gastrointestinal-pituitary axis. Objective: This …

Ghrelin in obesity, physiological and pharmacological considerations

P Álvarez-Castro, L Pena… - Mini reviews in medicinal …, 2013 - ingentaconnect.com
The aim of this review is to summarize the physiological and pharmacological aspects of
ghrelin. Obesity can be defined as an excess of body fat and is associated with significant …

Physiological, pathological and potential therapeutic roles of ghrelin

AF Leite-Moreira, JB Soares - Drug discovery today, 2007 - Elsevier
Ghrelin, a hormone that is produced mainly by the stomach, was identified originally as the
endogenous ligand of the growth hormone secretagogue (GHS) receptor. Ghrelin might also …

Ghrelin in the regulation of body weight and metabolism

TR Castaneda, J Tong, R Datta, M Culler… - Frontiers in …, 2010 - Elsevier
Ghrelin, a peptide hormone predominantly produced by the stomach, was isolated as the
endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is a potent …

[HTML][HTML] Ghrelin–physiological functions and regulation

MMI Abdalla - European endocrinology, 2015 - ncbi.nlm.nih.gov
Ghrelin is an orexigenic peptide predominantly secreted from the stomach and stimulates
appetite and growth hormone (GH) release. Studies have provided evidence that ghrelin …

Therapeutic potential of targeting the ghrelin pathway

G Colldén, MH Tschöp, TD Müller - International Journal of Molecular …, 2017 - mdpi.com
Ghrelin was discovered in 1999 as the endogenous ligand of the growth-hormone
secretagogue receptor 1a (GHSR1a). Since then, ghrelin has been found to exert a plethora …