Peptides with dual antimicrobial–anticancer activity: Strategies to overcome peptide limitations and rational design of anticancer peptides
Y Liscano, J Oñate-Garzón, JP Delgado - Molecules, 2020 - mdpi.com
Peptides are naturally produced by all organisms and exhibit a wide range of physiological,
immunomodulatory, and wound healing functions. Furthermore, they can provide with …
immunomodulatory, and wound healing functions. Furthermore, they can provide with …
Antimicrobial peptides with anticancer activity: Today status, trends and their computational design
M Kordi, Z Borzouyi, S Chitsaz, M hadi Asmaei… - Archives of Biochemistry …, 2023 - Elsevier
Some antimicrobial peptides have been shown to be able to inhibit the proliferation of
cancer cell lines. Various strategies for treating cancers with active peptides have been …
cancer cell lines. Various strategies for treating cancers with active peptides have been …
[HTML][HTML] Peptides with dual antimicrobial and anticancer activities
In recent years, the number of people suffering from cancer and multi-resistant infections has
increased, such that both diseases are already seen as current and future major causes of …
increased, such that both diseases are already seen as current and future major causes of …
Antimicrobial/anticancer peptides: Bioactive molecules and therapeutic agents
K Kardani, A Bolhassani - Immunotherapy, 2021 - Future Medicine
Antimicrobial peptides (AMPs) have been known as host-defense peptides. These cationic
and amphipathic peptides are relatively short (∼ 5–50 L-amino acids) with molecular weight …
and amphipathic peptides are relatively short (∼ 5–50 L-amino acids) with molecular weight …
From antimicrobial to anticancer peptides: the transformation of peptides
Y Qin, ZD Qin, J Chen, CG Cai, L Li… - Recent patents on …, 2019 - ingentaconnect.com
Background: Antimicrobial peptides play an important role in the innate immune system.
Possessing broad-spectrum antibacterial activity, antimicrobial peptides can quickly treat …
Possessing broad-spectrum antibacterial activity, antimicrobial peptides can quickly treat …
In Silico Models for Designing and Discovering Novel Anticancer Peptides
Use of therapeutic peptides in cancer therapy has been receiving considerable attention in
the recent years. Present study describes the development of computational models for …
the recent years. Present study describes the development of computational models for …
Anti-cancer peptides: Their current trends in the development of peptide-based therapy and anti-tumor drugs
A Lath, AR Santal, N Kaur, P Kumari… - Biotechnology and …, 2023 - Taylor & Francis
Human cancer remains a cause of high mortality throughout the world. The conventional
methods and therapies currently employed for treatment are followed by moderate-to-severe …
methods and therapies currently employed for treatment are followed by moderate-to-severe …
Rational design of hybrid peptides: a novel drug design approach
C Wang, C Yang, Y Chen, L Ma, K Huang - Current medical science, 2019 - Springer
Peptides play crucial roles in various physiological and pathological processes.
Consequently, the investigation of peptide-based drugs is a highlight in the research and …
Consequently, the investigation of peptide-based drugs is a highlight in the research and …
Peptide based antimicrobials: Design strategies and therapeutic potential
PK Hazam, R Goyal, V Ramakrishnan - Progress in Biophysics and …, 2019 - Elsevier
Therapeutic activity of antibiotics is noteworthy, as they are used in the treatment of microbial
infections. Regardless of their utility, there has been a steep decrease in the number of drug …
infections. Regardless of their utility, there has been a steep decrease in the number of drug …
Synthetic molecular evolution of antimicrobial peptides
Highlights•Various peptide design methods have facilitated peptide–drug
development.•Only a few peptide therapeutics have entered the antibiotic market in the past …
development.•Only a few peptide therapeutics have entered the antibiotic market in the past …
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