[PDF][PDF] Immune Modulation in HIV-Positive Neonates: Insights and Implications for Clinical Management
Neonatal HIV infection presents unique challenges in immune modulation and clinical
management. This review delves into the intricate dynamics of immune modulation in HIV …
management. This review delves into the intricate dynamics of immune modulation in HIV …
[PDF][PDF] HIV-Induced Immune Exhaustion in Neonates: A Review of Mechanisms and Implications
HIV infection during early life poses unique challenges to neonatal immune development,
potentially leading to immune exhaustion and increased susceptibility to infections. This …
potentially leading to immune exhaustion and increased susceptibility to infections. This …
[PDF][PDF] Immunodeficiency and Immune Reconstitution in Pediatric HIV: Mechanisms, Challenges, and Therapeutic Strategies
Pediatric HIV infection poses unique challenges to the developing immune system, leading
to profound immunodeficiency and impaired immune reconstitution despite antiretroviral …
to profound immunodeficiency and impaired immune reconstitution despite antiretroviral …
Early antiretroviral therapy in neonates with HIV-1 infection restricts viral reservoir size and induces a distinct innate immune profile
P Garcia-Broncano, S Maddali, KB Einkauf… - Science translational …, 2019 - science.org
Neonatal HIV-1 infection is associated with rapidly progressive and frequently fatal immune
deficiency if left untreated. Immediate institution of antiretroviral therapy (ART), ideally within …
deficiency if left untreated. Immediate institution of antiretroviral therapy (ART), ideally within …
[PDF][PDF] Unveiling the Role of Innate Immune Activation in Pediatric HIV: A Review
Pediatric HIV infection presents unique challenges due to the developing immune system
and distinctive clinical manifestations compared to adult HIV infection. Innate immune …
and distinctive clinical manifestations compared to adult HIV infection. Innate immune …
Immunology of pediatric HIV infection
NH Tobin, GM Aldrovandi - Immunological reviews, 2013 - Wiley Online Library
Most infants born to human immunodeficiency virus (HIV)‐infected women escape HIV
infection. Infants evade infection despite an immature immune system and, in the case of …
infection. Infants evade infection despite an immature immune system and, in the case of …
[PDF][PDF] Maternal Influence on Infant Immunological Responses to HIV: A Review
This paper critically examines the complex interplay between maternal factors and infant
immunological responses to Human Immunodeficiency Virus (HIV). The transmission of HIV …
immunological responses to Human Immunodeficiency Virus (HIV). The transmission of HIV …
Immunity to HIV in early life
M Muenchhoff, AJ Prendergast… - Frontiers in …, 2014 - frontiersin.org
The developing immune system is adapted to the exposure to a plethora of pathogenic and
non-pathogenic antigens encountered in utero and after birth, requiring a fine balance …
non-pathogenic antigens encountered in utero and after birth, requiring a fine balance …
Understanding viral and immune interplay during vertical transmission of HIV: implications for cure
O Amin, J Powers, KM Bricker, A Chahroudi - Frontiers in Immunology, 2021 - frontiersin.org
Despite the significant progress that has been made to eliminate vertical HIV infection, more
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …
Transfer of maternal antimicrobial immunity to HIV-exposed uninfected newborns
B Abu-Raya, KK Smolen, F Willems… - Frontiers in …, 2016 - frontiersin.org
The transfer of maternal immune factors to the newborn is critical for protection from
infectious disease in early life. Maternally acquired passive immunity provides protection …
infectious disease in early life. Maternally acquired passive immunity provides protection …