Calcium channel antagonists have become popular medications for the management of
hypertension. These agents belong to the diphenylalkylamine, benzothiazepine …

Multiple studies have demonstrated dihydropyridine calcium‐channel blocker (CCB) therapy
to be appropriate for the treatment of hypertension, as is reflected in treatment guidelines …

Calcium channel blockers (CCBs), which include both dihydropyridines such as nifedipine
and amlodipine and non‐dihydropyridines (verapamil and diltiazem), are among the most …

Closing Remarks: Current Position of Calcium Channel Antagonists in Hypertension – the Role
of Manidipine Page 1 Closing Remarks: Current Position of Calcium Channel Antagonists in …

Hypertension is one of the major risk factors for coronary heart disease and the most
important risk factor for cerebrovascular diseases (1). In most countries, almost 20% of the …

In all actual clinical guidelines, dihydropyridine calcium channel blockers (CCBs) belong to
the recommended first line antihypertensive drugs to treat essential hypertension. Several …

The prevalence of hypertension is increasing steadily in the US, particularly among African
Americans. It is now clear that a large proportion of patients are inadequately controlled, with …

As a drug class, calcium channel blockers encompass a heterogeneous group of
compounds with distinctive structures and pharmacologic characteristics. These agents are …

Japanese Society of Hypertension Committee published Guidelines for the Management of
Hypertension in 2009 (JSH2009). The first choices of antihypertensive drugs are calcium …

Antihypertensive drug classes such as thiazide diuretics, angiotensin-converting enzyme
inhibitors, β-adrenergic blocking agents, peripheral α1-antagonists, and central α2-agonists …