Background: Cellular diversity of the lung endothelium has not been systematically
characterized in humans. We provide a reference atlas of human lung endothelial cells …

Background: Endothelial cells (ECs) display considerable functional heterogeneity
depending on the vessel and tissue in which they are located. Whereas these functional …

The heterogeneity of endothelial cells (ECs) across tissues remains incompletely
inventoried. We constructed an atlas of> 32,000 single-EC transcriptomes from 11 mouse …

Endothelial cells line the inner surface of vasculature and play an important role in normal
physiology and disease progression. Although most tissue is known to have a …

Vascular diseases are major causes of death, yet our understanding of the cellular
constituents of blood vessels, including how differences in their gene expression profiles …

Studies have demonstrated the phenotypic heterogeneity of vascular endothelial cells (ECs)
within a vascular bed; however, little is known about how distinct endothelial subpopulations …

Objective—Endothelial cells (ECs) are a highly specialized cell type with marked diversity
between different organs or vascular beds. Cardiac ECs are an important player in cardiac …

Endothelial dysfunction is the common molecular basis of multiple human diseases, such as
atherosclerosis, diabetes, hypertension, and acute lung injury. Therefore, primary isolation …

Endothelial cells (ECs) constitute the inner lining of vascular beds in mammals and are
crucial for homeostatic regulation of blood vessel physiology, but also play a key role in …

Profiling gene expression in endothelial cells advances the understanding of normal
vascular physiology and disease processes involving angiogenesis. However, endothelial …