Loeys–Dietz syndrome: a primer for diagnosis and management
G MacCarrick, JH Black, S Bowdin, I El-Hamamsy… - Genetics in …, 2014 - nature.com
Loeys–Dietz syndrome is a connective tissue disorder predisposing individuals to aortic and
arterial aneurysms. Presenting with a wide spectrum of multisystem involvement, medical …
arterial aneurysms. Presenting with a wide spectrum of multisystem involvement, medical …
[HTML][HTML] Clinical features and complications of Loeys-Dietz syndrome: A systematic review
Abstract Introduction Loeys-Dietz syndrome (LDS) is a connective tissue disorder that arises
from mutations altering the transforming growth factor β signalling pathway. Due to the …
from mutations altering the transforming growth factor β signalling pathway. Due to the …
Loeys-dietz syndrome
BL Loeys - 1993 - books.google.com
In 2005, Bart Loeys and Harry Dietz described a new syndromic aneurysmal entity. Its
patients were typically characterized by a clinical triad that included hypertelorism (widely …
patients were typically characterized by a clinical triad that included hypertelorism (widely …
Musculoskeletal findings of Loeys-Dietz syndrome
G Erkula, PD Sponseller, LC Paulsen, GL Oswald… - JBJS, 2010 - journals.lww.com
Background: Loeys-Dietz syndrome is a recently recognized multisystemic disorder caused
by mutations in the genes encoding the transforming growth factor-beta receptor. It is …
by mutations in the genes encoding the transforming growth factor-beta receptor. It is …
Loeys-dietz syndrome
L Van Laer, H Dietz, B Loeys - Progress in heritable soft connective tissue …, 2014 - Springer
Loeys-Dietz syndrome is an autosomal dominant aortic aneurysm syndrome characterized
by multisystemic involvement. The most typical clinical triad includes hypertelorism, bifid …
by multisystemic involvement. The most typical clinical triad includes hypertelorism, bifid …
The Loeys–Dietz syndrome: an update for the clinician
C Van Hemelrijk, M Renard… - Current opinion in …, 2010 - journals.lww.com
LDS is caused by mutation in the genes encoding the transforming growth factor beta
receptor 1 and 2 (TGFBR1 and TGFRB2) and is characterized by aggressive aortic/arterial …
receptor 1 and 2 (TGFBR1 and TGFRB2) and is characterized by aggressive aortic/arterial …
[HTML][HTML] Cardiovascular operations for Loeys-Dietz syndrome: intermediate-term results
Abstract Objectives Early experience with Loeys-Dietz syndrome (LDS) suggested an
aggressive aortopathy with high risk of aneurysm dissection and rupture at young ages and …
aggressive aortopathy with high risk of aneurysm dissection and rupture at young ages and …
Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis
EM Gallo, DC Loch, JP Habashi… - The Journal of …, 2014 - Am Soc Clin Investig
Loeys-Dietz syndrome (LDS) is a connective tissue disorder that is characterized by a high
risk for aneurysm and dissection throughout the arterial tree and phenotypically resembles …
risk for aneurysm and dissection throughout the arterial tree and phenotypically resembles …
Aneurysm syndromes caused by mutations in the TGF-β receptor
BL Loeys, U Schwarze, T Holm… - … England Journal of …, 2006 - Mass Medical Soc
Background The Loeys–Dietz syndrome is a recently described autosomal dominant aortic-
aneurysm syndrome with widespread systemic involvement. The disease is characterized by …
aneurysm syndrome with widespread systemic involvement. The disease is characterized by …
Histopathologic findings in ascending aortas from individuals with Loeys-Dietz syndrome (LDS)
Loeys-Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder resulting
from genetic mutations in the transforming growth factor β receptors 1 and 2 (TGFBR1 and …
from genetic mutations in the transforming growth factor β receptors 1 and 2 (TGFBR1 and …