Polymer-lipid hybrid nanoparticles, PMONPs, were developed to improve the oral
absorption of cabazitaxel (CTX), a semi-synthetic taxane derivative, by overcoming multiple …

To ensure that antitumor drugs can be effectively transported across intestinal barrier and
then quickly released in tumor cells, mixed polymeric micelles (Mix-PMs) were designed and …

Here we report the development and evaluation of cysteine-modified nanostructured lipid
carriers (NLCs) for oral delivery of docetaxel (DTX). The NLCs ensure high encapsulation …

In spite of being a very potent and promising drug against many types of cancer, docetaxel
suffers the disadvantage of low solubility and poor bioavailability rendering it unsuitable for …

In this article, a new type of carboxymethyl chitosan/phospholipid bilayer-capped
mesoporous carbon nanomatrix (CCS/PL/MC) was fabricated as a potential nano-drug …

Oral delivery of anticancer drugs remains challenging despite the most convenient route of
drug administration. Hydrophobicity and nonspecific toxicities of anticancer agents are major …

Bioadhesive nanoparticles based on poly (vinyl methyl ether/maleic anhydride)(PVMMA)
and poly (ethylene glycol) methyl ether-b-poly (d, l-lactic acid)(mPEG-b-PLA) were produced …

Purpose This study was carried out to determine the biodistribution profiles and tumor
localization potential of poly (ethylene oxide)(PEO)-modified poly (β-amino ester)(PbAE) as …

Docetaxel is a potent anticancer drug, but development of an oral formulation has been
hindered mainly due to its poor oral bioavailability. In this study, solid lipid nanoparticles …

The objective of the current study was to explore the potential of nanostructured lipid carriers
(NLC) for oral delivery of docetaxel (DTX) and investigate the absorption mechanism in vivo …