[HTML][HTML] Uremic toxins and cardiovascular risk in chronic kidney disease: what have we learned recently beyond the past findings?

C El Chamieh, S Liabeuf, Z Massy - Toxins, 2022 - mdpi.com
Patients with chronic kidney disease (CKD) have an elevated prevalence of atheromatous
(ATH) and/or non-atheromatous (non-ATH) cardiovascular disease (CVD) due to an array of …

[HTML][HTML] Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets

YJ Lim, NA Sidor, NC Tonial, A Che, BL Urquhart - Toxins, 2021 - mdpi.com
Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …

Uraemic toxins and cardiovascular disease across the chronic kidney disease spectrum: an observational study

M Rossi, K Campbell, D Johnson, T Stanton… - Nutrition, Metabolism …, 2014 - Elsevier
Background and aims There is a growing body of evidence supporting the nephrovascular
toxicity of indoxyl sulphate (IS) and p-cresyl sulphate (PCS). Nonetheless, a comprehensive …

From old uraemic toxins to new uraemic toxins: place of 'omics'

ZA Massy, S Liabeuf - Nephrology Dialysis Transplantation, 2018 - academic.oup.com
Uraemic toxins seem to play an important role in the genesis of cardiovascular and renal
damage in chronic kidney disease patients. This short article is divided into two thematic …

[HTML][HTML] Gut microbiota and cardiovascular uremic toxicities

MT Velasquez, P Centron, I Barrows, R Dwivedi… - Toxins, 2018 - mdpi.com
Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in
patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients …

[HTML][HTML] Food-derived uremic toxins in chronic kidney disease

M Lauriola, R Farré, P Evenepoel, SA Overbeek… - Toxins, 2023 - mdpi.com
Patients with chronic kidney disease (CKD) have a higher cardiovascular risk compared to
the average population, and this is partially due to the plasma accumulation of solutes …

Cardiovascular burden associated with uremic toxins in patients with chronic kidney disease

H Moradi, DA Sica, K Kalantar-Zadeh - American journal of nephrology, 2013 - karger.com
Background: Retention of uremic toxins in patients with chronic kidney disease (CKD)
negatively affects multiple organ systems, including the cardiovascular system, resulting in …

[HTML][HTML] Molecular mechanisms underlying the cardiovascular toxicity of specific uremic solutes

JD Ravid, VC Chitalia - Cells, 2020 - mdpi.com
Mounting evidence strongly suggests a causal link between chronic kidney disease (CKD)
and cardiovascular disease (CVD). Compared with non-CKD patients, patients with CKD …

Uremia retention molecules and clinical outcomes

FC Barreto, DV Barreto, MEF Canziani - Expanded Hemodialysis, 2017 - karger.com
Chronic kidney disease is characterized by the accumulation of organic compounds in the
bloodstream that may exert a variety of toxic effects in the body. These compounds …

[HTML][HTML] Lipid Profile Is Negatively Associated with Uremic Toxins in Patients with Kidney Failure—A Tri-National Cohort

S Hobson, H de Loor, K Kublickiene, J Beige… - Toxins, 2022 - mdpi.com
Patients with kidney failure (KF) have a high incidence of cardiovascular (CV) disease, partly
driven by insufficient clearance of uremic toxins. Recent investigations have questioned the …