Mesenchymal stem cell-derived antimicrobial peptides as potential anti-neoplastic agents: new insight into anticancer mechanisms of stem cells and exosomes

K Moeinabadi-Bidgoli, M Rezaee… - Frontiers in Cell and …, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs), as adult multipotent cells, possess considerable
regenerative and anti-neoplastic effects, from inducing apoptosis in the cancer cells to …

Antimicrobial activity of mesenchymal stem cells: current status and new perspectives of antimicrobial peptide-based therapies

F Alcayaga-Miranda, J Cuenca, M Khoury - Frontiers in immunology, 2017 - frontiersin.org
While mesenchymal stem cells (MSCs)-based therapy appears to be promising, there are
concerns regarding possible side effects related to the unwanted suppression of …

Dissecting the relationship between antimicrobial peptides and mesenchymal stem cells

AÉ Silva-Carvalho, MH Cardoso, T Alencar-Silva… - Pharmacology & …, 2022 - Elsevier
Among the various biological properties presented by Mesenchymal Stem Cells (MSCs),
their ability to control the immune response and fight pathogen infection through the …

Mesenchymal stem cell: a friend or foe in anti-tumor immunity

CR Harrell, A Volarevic, VG Djonov, N Jovicic… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are self-renewable, multipotent stem cells that regulate the
phenotype and function of all immune cells that participate in anti-tumor immunity. MSCs …

Emerging roles of mesenchymal stem/stromal-cell-derived extracellular vesicles in cancer therapy

A Nicodemou, S Bernátová, M Čeháková, Ľ Danišovič - Pharmaceutics, 2023 - mdpi.com
Despite the tremendous efforts of many researchers and clinicians, cancer remains the
second leading cause of mortality worldwide. Mesenchymal stem/stromal cells (MSCs) are …

Arming mesenchymal stromal/stem cells against cancer: has the time come?

G Golinelli, I Mastrolia, B Aramini, V Masciale… - Frontiers in …, 2020 - frontiersin.org
Since mesenchymal stromal/stem cells (MSCs) were discovered, researchers have been
drawn to study their peculiar biological features, including their immune privileged status …

The Role of Mesenchymal Stem Cells and Exosomes in Tumor Development and Targeted Antitumor Therapies

E Yang, S Jing, Y Wang, H Wang… - Stem Cells …, 2023 - Wiley Online Library
Mesenchymal stem cells (MSCs) can be isolated from various tissues in adults and
differentiated into cells of the osteoblasts, adipocytes, chondrocytes, and myocytes …

Effect of mesenchymal stem cells‐derived exosomes on tumor microenvironment: tumor progression versus tumor suppression

S Shojaei, SM Hashemi, H Ghanbarian… - Journal of cellular …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells with the potential to differentiate into
different cell types. Owing to their immunosuppressive and anti‐inflammatory properties …

Anticancer Mechanisms and Potential Anticancer Applications of Antimicrobial Peptides and Their Nano Agents

Z Dong, X Zhang, Q Zhang… - International Journal …, 2024 - Taylor & Francis
Traditional chemotherapy is one of the main methods of cancer treatment, which is largely
limited by severe side effects and frequent development of multi-drug resistance by cancer …

[HTML][HTML] The bad and the good of mesenchymal stem cells in cancer: Boosters of tumor growth and vehicles for targeted delivery of anticancer agents

U Galderisi, A Giordano, MG Paggi - World journal of stem cells, 2010 - ncbi.nlm.nih.gov
In cancer biology, mesenchymal stem cells (MSCs) display aspects that can appear
contradictory. On one hand, these cells possess several features which give them the ability …