Lichen planus (LP) is a common inflammatory skin disease of unknown etiology. Reports of
a common transactivation of quiescent human endogenous retroviruses (HERVs) support …

Background The origin of psoriasis, a chronic inflammatory skin disease involving
keratinocyte proliferation, immune disturbances and complex inheritance, remains unknown …

Human endogenous retrovirus (HERV) sequences make up at least 8% of the human
genome. Transcripts originating from these loci as well as proteins encoded by them have …

Background Psoriasis is a common inflammatory skin disease characterized by uncontrolled
proliferation of keratinocytes and recruitment of T lymphocytes into the skin. The possible …

Results: In PBMCs we found a statistically significant decrease of transcription of HERV-E
pol, while HERV-K env, HERV-R pol-env, and HERV-W env were found to be up-regulated …

Pemphigus is a severe, potentially life-threatening autoimmune blistering mucocutaneous
disease which establishes with autoreactive IgG antibodies that target cellular adhesions …

Background Psoriasis is a multifactorial, chronic disease of skin affecting 2-3% of the world's
population. Genetic studies of psoriasis have identified a number of susceptibility genes that …

Toll-like receptors (TLRs) recognize specific microbial products in the innate immune
response. TLR3, a double-stranded RNA sensor, is thought to have an important role in viral …

Background Lichen planus (LP) is an inflammatory disease of the skin and oral mucosa. The
association of LP and chronic hepatitis C virus (HCV) is well established, with variable …

Background Lichen planus (LP) is a common inflammatory skin disease of unknown
aetiology. Viral causes have been suggested. Objectives To find candidate viruses …