Modulating the antioxidant response for better oxidative stress-inducing therapies: How to take advantage of two sides of the same medal?

P Shaw, N Kumar, M Sahun, E Smits, A Bogaerts… - Biomedicines, 2022 - mdpi.com
Oxidative stress-inducing therapies are characterized as a specific treatment that involves
the production of reactive oxygen and nitrogen species (RONS) by external or internal …

[PDF][PDF] The interplay of oxidative stress and inflammation: mechanistic insights and therapeutic potential of antioxidants

AM Mahmoud, FL Wilkinson, MA Sandhu… - … Medicine and Cellular …, 2021 - researchgate.net
Oxidative stress is caused by the overproduction of Reactive Oxygen Species (ROS) and
diminished cellular antioxidant defenses. Under physiological conditions, ROS are involved …

[PDF][PDF] The Role of Natural and Synthetic Antioxidants in Modulating Oxidative Stress in Drug‐Induced Injury and Metabolic Disorders 2020

AM Mahmoud, FL Wilkinson, AP Lightfoot… - … Medicine and Cellular …, 2021 - researchgate.net
Oxidative stress is an imbalance in cellular redox reactions that plays a key role in the
pathogenesis of metabolic disorders and drug-induced injury. Oxidative stress is the result of …

Oxidative stress in disease and aging: mechanisms and therapies 2018

C Cabello-Verrugio, C Vilos… - … medicine and cellular …, 2018 - ncbi.nlm.nih.gov
Among the key factors influencing human health are the chronic diseases and aging, which
have been increasing in the last decades. These pathological states are produced by …

[HTML][HTML] Strategies for modulating oxidative stress under diverse physiological and pathological conditions

K Szewczyk-Golec, J Czuczejko… - … Medicine and Cellular …, 2018 - ncbi.nlm.nih.gov
Numerous physiological and pathological conditions are related to the augmentation of
oxidative stress. The weakened antioxidant defense and the increased production of …

Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species

L He, T He, S Farrar, L Ji, T Liu, X Ma - Cellular Physiology and …, 2017 - karger.com
Reactive oxygen species (ROS) are produced by living cells as normal cellular metabolic
byproduct. Under excessive stress conditions, cells will produce numerous ROS, and the …

Potential use of antioxidants for the treatment of chronic inflammatory diseases

AV Blagov, VI Summerhill, VN Sukhorukov… - Frontiers in …, 2024 - frontiersin.org
The excessive production of various reactive oxidant species over endogenous antioxidant
defense mechanisms leads to the development of a state of oxidative stress, with serious …

Metabolic implications of oxidative stress and inflammatory process in SARS-CoV-2 pathogenesis: therapeutic potential of natural antioxidants

GE Forcados, A Muhammad, OO Oladipo… - Frontiers in Cellular …, 2021 - frontiersin.org
COVID-19 is a zoonotic disease with devastating economic and public health impacts
globally. Being a novel disease, current research is focused on a clearer understanding of …

[HTML][HTML] Modulating oxidative stress in drug-induced injury and metabolic disorders: the role of natural and synthetic antioxidants

AM Mahmoud, FL Wilkinson, MA Sandhu… - … Medicine and Cellular …, 2019 - ncbi.nlm.nih.gov
Oxidative stress is an imbalance in cellular redox reactions which plays a key role in the
pathogenesis of metabolic disorders and drug-induced injury [1–3]. Oxidative stress is the …

Targeting free radicals in oxidative stress-related human diseases

P Poprac, K Jomova, M Simunkova, V Kollar… - Trends in …, 2017 - cell.com
Cancer and Alzheimer's disease (AD) are characterized by (i) opposing biological
mechanisms,(ii) an inverse correlation between their incidences, and (iii) oxidative stress …