Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis

B Shang, Y Liu, S Jiang, Y Liu - Scientific reports, 2015 - nature.com
The prognostic value of FoxP3+ regulatory T cells (Tregs) in cancer remains controversial.
We did a meta-analysis to assess the prognostic effect of FoxP3+ Treg across different types …

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

P Salama, M Phillips, F Grieu, M Morris… - Journal of clinical …, 2009 - ascopubs.org
Purpose To determine the prognostic significance of FOXP3+ lymphocyte (Treg) density in
colorectal cancer compared with conventional histopathologic features and with CD8+ and …

[HTML][HTML] FoxP3+ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets

R Saleh, E Elkord - Cancer letters, 2020 - Elsevier
T Regulatory cells (Tregs) can have both protective and pathological roles. They maintain
immune homeostasis and inhibit immune responses in various diseases, including cancer …

Prognostic Value of Tumor-Infiltrating FoxP3+ T Cells in Gastrointestinal Cancers: A Meta Analysis

Y Huang, H Liao, Y Zhang, R Yuan, F Wang, Y Gao… - PloS one, 2014 - journals.plos.org
Purpose Tumor-infiltrating FoxP3+ T cells have been reported in various human tumors,
which impaired cell-mediated immunity and promoted disease progression. However, its …

[HTML][HTML] Prognostic value of tumor-infiltrating Foxp3+ regulatory T cells in patients with breast cancer: a meta-analysis

Y Zhou, N Shao, N Aierken, C Xie, R Ye, X Qian… - Journal of …, 2017 - ncbi.nlm.nih.gov
Purpose: The prognostic value of tumor-infiltrating Foxp3+ regulatory T cells (Tregs) in
breast cancer remains controversial. Therefore, we performed this meta-analysis to …

Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients

J Zhou, T Ding, W Pan, L Zhu, L Li… - International journal of …, 2009 - Wiley Online Library
Immunosuppression mediated by regulatory T cells (Tregs) is a key facilitator of tumor
immune evasion, but the source of these Tregs and their contribution to human cancer …

The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature

RJ Deleeuw, SE Kost, JA Kakal, BH Nelson - Clinical cancer research, 2012 - AACR
Abstract CD8+ tumor-infiltrating lymphocytes (TIL) are associated with survival in a variety of
cancers. A second subpopulation of TIL, defined by forkhead box protein P3 (FoxP3) …

In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer

C Loddenkemper, M Schernus, M Noutsias… - Journal of translational …, 2006 - Springer
The immune system spontaneously responds to tumor-associated antigens in peripheral
blood of colorectal cancer (CRC) patients. Regulatory T cells (Treg) are suspected of …

Incidence and Prognostic Impact of FoxP3+ Regulatory T Cells in Human Gliomas

AB Heimberger, M Abou-Ghazal, C Reina-Ortiz… - Clinical Cancer …, 2008 - AACR
Purpose: The incidence of regulatory T cells (Treg) in intrinsic central nervous system
malignancies is unknown. Immunotherapeutic approaches that inhibit the Treg population …

Worse outcome in breast cancer with higher tumor-infiltrating FOXP3+ Tregs: a systematic review and meta-analysis

J Shou, Z Zhang, Y Lai, Z Chen, J Huang - BMC cancer, 2016 - Springer
Abstract Background Forkhead box P3 (FOXP3) is known as the optimum maker for
regulatory T cells (Tregs), which are conventionally thought to induce immune tolerance to …