Abstract NAD (P) H-dependent oxidoreductases catalyze the reduction or oxidation of a
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …

Biocatalytic oxidations can offer clear advantages compared to chemically catalyzed
oxidations in terms of chemo, regio and stereoselectivity as well as a reduced environmental …

The topic of synthetic nicotinamide cofactor analogues is resurfacing as new approaches
are being explored, especially in the areas of organic chemistry and biocatalysis. By …

Significance: The oxidative stress, resulting from an imbalance in the production and
scavenging of reactive oxygen species (ROS), is known to be involved in the development …

The ubiquitous redox cofactors nicotinamide adenine dinucleotides [NAD and NADP] are
very similar molecules, despite their participation in substantially different biochemical …

The NADPH oxidase of professional phagocytes is a crucial component of the innate
immune response due to its fundamental role in the production of reactive oxygen species …

Background The reactive oxygen-generating N ADPH ox idases (Noxes) function in a variety
of biological roles, and can be broadly classified into those that are regulated by subunit …

Reactive oxygen species (ROS) are conventionally regarded as inevitable deleterious by-
products in aerobic metabolism with a few exceptions such as their significant role in host …

Increased oxidative stress plays an important role in the pathophysiology of many diseases
such as atherosclerosis, diabetes mellitus, myocardial infarction and heart failure. In addition …

The FAD-dependent NAD (P) H oxidase from Lactobacillus sanfrancisensis (L. san-Nox2)
catalyzes the oxidation of 2 equivalents of either NADH or NADPH and reduces 1 equivalent …