Masseter corticomotor excitability is decreased after intramuscular administration of nerve growth factor

YM Costa, FG Exposto, M Kothari… - … Journal of Pain, 2019 - Wiley Online Library
Background Quantification of motor‐evoked potentials (MEPs) can contribute to better
elucidate the central modulation of motor pathways in response to nociceptive inputs. The …

Nerve growth factor-evoked masseter muscle sensitization and perturbation of jaw motor function in healthy women.

P Svensson, E Castrillon… - Journal of orofacial …, 2008 - search.ebscohost.com
Aim: To replicate and extend previous findings of nerve growth factor (NGF)-induced
mechanical sensitization in healthy young men to women and test for associations between …

Injection of nerve growth factor into human masseter muscle evokes long-lasting mechanical allodynia and hyperalgesia

P Svensson, BE Cairns, K Wang, L Arendt-Nielsen - Pain, 2003 - Elsevier
Nerve growth factor (NGF) is a neurotrophic protein with a pivotal role in development and
maintenance of the nervous system on one side and inflammatory and neuropathic pain …

[PDF][PDF] Influence of intramuscular nerve growth factor injection on the response properties of rat masseter muscle afferent fibers.

MK Mann, XD Dong, P Svensson… - Journal of orofacial …, 2006 - researchgate.net
Aims: To investigate whether local administration of nerve growth factor (NGF) decreases
the mechanical threshold (MT) of putative nociceptive masseter afferent fibers as part of its …

Comparison of Pain-Generated Functional Outcomes in Experimental Models of Delayed-Onset Muscle Soreness and Nerve Growth Factor Injection of the Masticatory …

Y Zhang, FG Exposto, A Grigoriadis… - Journal of Oral & …, 2020 - search.ebscohost.com
Aims: To compare two pain models of myalgic TMD, delayed-onset muscle soreness
(DOMS) and injections of nerve growth factor (NGF), in terms of pain-related and motor …

Effects of nerve growth factor experimentally-induced craniofacial muscle sensitization on referred pain frequency and number of headache days: a double-blind …

FG Exposto, M Masuda, EE Castrillon… - …, 2018 - journals.sagepub.com
Objective To assess if repeated intramuscular injections of nerve growth factor into the
temporalis and masseter muscles increase mechanical sensitivity and entropy scores …

[HTML][HTML] Sex-related differences in response to masseteric injections of glutamate and nerve growth factor in healthy human participants

AM Alhilou, A Shimada, CI Svensson, P Svensson… - Scientific reports, 2021 - nature.com
The neurophysiological mechanisms underlying NGF-induced masseter muscle
sensitization and sex-related differences in its effect are not well understood in humans …

Effects of NGF-induced muscle sensitization on proprioception and nociception

P Svensson, K Wang, L Arendt-Nielsen… - Experimental brain …, 2008 - Springer
Temporomandibular disorders (TMDs) are associated with perturbation of proprioceptive
and nociceptive function. Recent studies have shown that injection of the neurotrophic …

[HTML][HTML] Functional change in experimental allodynia after glutamate-induced pain in the human masseter muscle

A Shimada, AM Alhilou, P Svensson, M Ernberg… - Frontiers in oral …, 2020 - frontiersin.org
Background: Glutamate, as well as nerve growth factor (NGF), is involved in nociception
from peripheral tissues, such as muscles. However, the potential interaction between …

NGF-induced mechanical sensitization of the masseter muscle is mediated through peripheral NMDA receptors

H Wong, I Kang, XD Dong, N Christidis, M Ernberg… - Neuroscience, 2014 - Elsevier
Intramuscular injection of nerve growth factor (NGF) in healthy humans mimics some of the
symptoms of myofascial temporomandibular disorders (M-TMD). We hypothesized that NGF …