[HTML][HTML] Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
E Ku, L Del Vecchio, KU Eckardt, VH Haase… - Kidney international, 2023 - Elsevier
Anemia is common in patients with chronic kidney disease and is associated with a high
burden of morbidity and adverse clinical outcomes. In 2012, Kidney Disease: Improving …
burden of morbidity and adverse clinical outcomes. In 2012, Kidney Disease: Improving …
[HTML][HTML] Anemia in chronic kidney disease: from pathophysiology and current treatments, to future agents
J Portolés, L Martín, JJ Broseta, A Cases - Frontiers in Medicine, 2021 - frontiersin.org
Anemia is a common complication in chronic kidney disease (CKD), and is associated with a
reduced quality of life, and an increased morbidity and mortality. The mechanisms involved …
reduced quality of life, and an increased morbidity and mortality. The mechanisms involved …
Effect of hypoxia-inducible factor-prolyl hydroxylase inhibitors on anemia in patients with CKD: a meta-analysis of randomized controlled trials including 2804 patients
B Wang, Q Yin, YC Han, M Wu, ZL Li, Y Tu, L Zhou… - Renal failure, 2020 - Taylor & Francis
Hypoxia-inducible factor-prolyl hydroxylase inhibitors (HIF-PHIs) are orally active first-in-
class new generation drugs for renal anemia. This extensive meta-analysis of randomized …
class new generation drugs for renal anemia. This extensive meta-analysis of randomized …
[HTML][HTML] Evolving strategies in the treatment of anaemia in chronic kidney disease: the HIF-prolyl hydroxylase inhibitors
F Locatelli, R Minutolo, L De Nicola, L Del Vecchio - Drugs, 2022 - Springer
Chronic kidney disease (CKD) affects approximately 10% of the worldwide population;
anaemia is a frequent complication. Inadequate erythropoietin production and absolute or …
anaemia is a frequent complication. Inadequate erythropoietin production and absolute or …
Efficacy and safety of HIF prolyl-hydroxylase inhibitor vs epoetin and darbepoetin for anemia in chronic kidney disease patients not undergoing dialysis: A network …
Q Zheng, H Yang, L Sun, R Wei, X Fu, Y Wang… - Pharmacological …, 2020 - Elsevier
Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a new class of oral
medicines being developed for the treatment of anemia in chronic kidney disease (CKD) …
medicines being developed for the treatment of anemia in chronic kidney disease (CKD) …
Future perspectives of anemia management in chronic kidney disease using hypoxia-inducible factor-prolyl hydroxylase inhibitors
M Sugahara, T Tanaka, M Nangaku - Pharmacology & Therapeutics, 2022 - Elsevier
For the past 3 decades, erythropoiesis-stimulating agents (ESA) in conjunction with iron
supplementation has been the mainstay of treatment for anemia in chronic kidney disease …
supplementation has been the mainstay of treatment for anemia in chronic kidney disease …
Recommendations by the Asian Pacific society of nephrology (APSN) on the appropriate use of HIF‐PH inhibitors
Renal anaemia is a common and important complication in patients with chronic kidney
disease (CKD). The current standard‐of‐care treatment for renal anaemia in CKD patients …
disease (CKD). The current standard‐of‐care treatment for renal anaemia in CKD patients …
Hypoxia-inducible factor–prolyl hydroxylase inhibitors in the treatment of anemia of chronic kidney disease
VH Haase - Kidney international supplements, 2021 - Elsevier
Hypoxia-inducible factor–prolyl hydroxylase domain inhibitors (HIF-PHIs) are a promising
new class of orally administered drugs currently in late-stage global clinical development for …
new class of orally administered drugs currently in late-stage global clinical development for …
[HTML][HTML] Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference
In chronic kidney disease, anemia and disordered iron homeostasis are prevalent and
associated with significant adverse consequences. In 2012, Kidney Disease: Improving …
associated with significant adverse consequences. In 2012, Kidney Disease: Improving …
Long‐term efficacy and safety of hypoxia‐inducible factor prolyl hydroxylase inhibitors in anaemia of chronic kidney disease: A meta‐analysis including 13,146 …
H Chen, Q Cheng, J Wang, X Zhao… - Journal of clinical …, 2021 - Wiley Online Library
What is known and objective Previous studies based on small‐sample clinical data proved
that short‐term use of hypoxia‐inducible factor prolyl hydroxylase (HIF‐PHD) inhibitors …
that short‐term use of hypoxia‐inducible factor prolyl hydroxylase (HIF‐PHD) inhibitors …
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