Innate immune responses to acute viral infection during pregnancy

EF Cornish, I Filipovic, F Åsenius, DJ Williams… - Frontiers in …, 2020 - frontiersin.org
Immunological adaptations in pregnancy allow maternal tolerance of the semi-allogeneic
fetus but also increase maternal susceptibility to infection. At implantation, the endometrial …

The unique immunological and microbial aspects of pregnancy

G Mor, P Aldo, AB Alvero - Nature Reviews Immunology, 2017 - nature.com
The comparison of the immunological state of pregnancy to an immunosuppressed host–
graft model continues to lead research and clinical practice to ill-defined approaches. This …

Contributions of maternal and fetal antiviral immunity in congenital disease

LJ Yockey, C Lucas, A Iwasaki - Science, 2020 - science.org
Viral infections during pregnancy can have devastating consequences on pregnancy
outcomes, fetal development, and maternal health. In this review, we examine fetal and …

How immune mechanisms are affected by pregnancy

P Luppi - Vaccine, 2003 - Elsevier
Pregnancy requires physiologic adaptations in all maternal systems, including the immune
system. This process is complex and includes modifications at different levels and …

Role of inflammation in virus pathogenesis during pregnancy

A Chudnovets, J Liu, H Narasimhan, Y Liu… - Journal of …, 2020 - Am Soc Microbiol
Viral infections during pregnancy lead to a spectrum of maternal and fetal outcomes, ranging
from asymptomatic disease to more critical conditions presenting with severe maternal …

Viral infections during pregnancy: the big challenge threatening maternal and fetal health

W Yu, X Hu, B Cao - Maternal-Fetal Medicine, 2022 - mednexus.org
Viral infections during pregnancy are associated with adverse pregnancy outcomes,
including maternal and fetal mortality, pregnancy loss, premature labor, and congenital …

Immunology and the immunological response in pregnancy

R Orefice - Best practice & research Clinical obstetrics & …, 2021 - Elsevier
The immune system in humans is a complex system capable of discriminating self from non-
self, and mounting appropriate allogenic immune responses to protect themselves from …

Host defense and tolerance: unique challenges in the placenta

VB Zeldovich, AI Bakardjiev - 2012 - journals.plos.org
Mammalian gestation creates an immunological paradox wherein the body must balance
tolerance of an allogeneic fetus with protection against invading pathogens. Pregnancy has …

Understanding the immune system in fetal protection and maternal infections during pregnancy

T Hussain, G Murtaza, DH Kalhoro… - Journal of …, 2022 - Wiley Online Library
The fetal‐maternal immune system determines the fate of pregnancy. The trophoblast cells
not only give an active response against external stimuli but are also involved in secreting …

Gimme shelter: the immune system during pregnancy

A Munoz‐Suano, AB Hamilton… - Immunological reviews, 2011 - Wiley Online Library
Antigen‐presenting molecules vary between individuals of the same species, making it more
difficult for pathogens to evade immune recognition and spread through the whole …