Alkane monooxygenase (AlkB) is a widely occurring integral membrane metalloenzyme that
catalyzes the initial step in the functionalization of recalcitrant alkanes with high terminal …

Alkanes are the most energy-rich form of carbon and are widely dispersed in the
environment. Their transformation by microbes represents a key step in the global carbon …

The alkane hydroxylase AlkB of Pseudomonas putida GPo1 is typical of a large class of
membrane-spanning diiron oxygenases that catalyze hydroxylation, epoxidation, and …

Alkane-oxidizing enzymes play an important role in the global carbon cycle. Alkane
monooxygenase (AlkB) oxidizes most of the medium-chain length alkanes in the …

Pseudomonas putida GPo1 alkane hydroxylase (AlkB) is an integral membrane protein that
catalyses the hydroxylation of medium-chain alkanes (C3–C12). 1-Octyne irreversibly …

Alkane monooxygenase (AlkB) is a non-heme diiron enzyme that catalyzes the
hydroxylation of alkanes. It is commonly found in alkanotrophic organisms that can live on …

Conspectus Every year, perhaps as much as 800 million tons of hydrocarbons enters the
environment; alkanes make up a large percentage of it. Most are transformed by organisms …

Interest in understanding the environmental distribution of the alkane monooxygenase
(AlkB) enzyme led to the identification of over 100 distinct alkane monooxygenase (AlkB) …

Enzymes of the AlkB and CYP153 families catalyze the first step in the catabolism of medium-
chain-length alkanes, selective oxidation of the alkane to the 1-alkanol, and enable their …

In this issue of the Journal of Bacteriology, van Beilen and colleagues (20) propose an
elegant model that explains how members of the family of integral membrane alkane …