Since their identification in 1994, cancer stem cells (CSCs) have been objects of intensive
study. Their properties and mechanisms of formation have become a major focus of current …

Cancer stem cells (CSCs) are a class of pluripotent cells that have been observed in most
types of solid and hematologic cancers. CSCs have been shown in numerous cancer …

Modern tumor therapy has achieved considerable progress, but many tumors remain
refractory to treatment or relapse following initial remission. Recent evidence points to one …

Cancer stem cells (CSCs) have been demonstrated in a variety of tumors and are thought to
act as a clonogenic core for the genesis of new tumor growth. This small subpopulation of …

Different mechanisms contribute to intratumor heterogeneity, including genetic mutations,
the microenvironment, and the existence of subpopulations of cancer cells with increased …

Cancer stem cells (CSCs) are a subpopulation of tumour cells that possess the stem cell
properties of self-renewal and differentiation. Stem cells might be the target cells responsible …

Cancer stem cells (CSC s) are undifferentiated cancer cells with a high tumorigenic activity,
the ability to undergo self‐renewal, and a multilineage differentiation potential. Cancer stem …

A small subpopulation of cells within the bulk of tumors share features with somatic stem
cells, in that, they are capable of self-renewal, they differentiate, and are highly resistant to …

Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …

Over a decade of research has confirmed the critical role of cancer stem-like cells (CSCs) in
tumor initiation, chemoresistance, and metastasis. Increasingly, CSC hierarchies have …